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Aim: To identify the genes and non-coding RNAs (ncRNAs) involved in the neuroprotective actions of a dietary anti-oxidant (saffron) and of photobiomodulation. Methods: We used a previously published assay of photoreceptor damage, in which albino Sprague Dawley rats raised in dim cyclic illumination ...
ORGANISM(S): Rattus norvegicus 
The purpose of the experiment was to determine whole transcriptome changes after spinal cord injury (SCI) to understand how photobiomodulation promotes neuroprotection and functional recovery. SCI was performed at the thoracic (T) level T8, by crushing the dorsal columns using a calibrated watchmake...
ORGANISM(S): Rattus norvegicus 
Photobiomodulation ameliorates Alexander disease through AMPK/mTOR-mediated mitophagy
Transcriptomic sequencing reveals gene expression profiles underlying photobiomodulation-mediated amelioration of hypobaric hypoxia-induced synaptic plasticity deficits in mice
Photobiomodulation is a neuromodulation technique that employs lasers and light-emitting diodes to stimulate neural activity and improve brain function, demonstrating favorable clinical outcomes in the treatment of various neurological and neuropsychiatric disorders. In this study, we applied 1064 n...
ORGANISM(S): Mus musculus 
2026-03-31 | GSE325653 | GEO
Genomics
photobiomodulation changes to Parkinson's microbiome
Photobiomodulation mitigates LPS-induced astrocyte neuroinflammation via the STAT5A/SOCS3 axis
Purpose: This study uses transcriptome analysis (RNA-seq) to study the effects of photobiomodulation therapy on classically activated M1 macrophages induced by LPS and IFN-γ.
ORGANISM(S): Mus musculus 
2021-11-20 | GSE188917 | GEO
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