Sort   by:  
 Page size 

INTRODUCTION: Since the beginning of the SARS-CoV-2 pandemic in December 2019 multiple metabolomics studies have proposed predictive biomarkers of infection severity and outcome. Whilst some trends have emerged, the findings remain intangible and uninformative when it comes to n...

2024-04-23 | MTBLS7429 | MetaboLights
Background: Information on the carcinogenic potential of chemicals is only availably for High Production Volume products. There is however, a pressing need for alternative methods allowing for the chronic toxicity of substances, including carcinogenicity, to be detected earlier and more reliably. He...
ORGANISM(S): Mus musculus 
Predictive Models of Drug Response in Canine Osteosarcoma: A Prospective Clinical Trial Testing the COXEN Approach
14 PDX models of pmCRC were established, including 9 matched PD3D/PDX models, and treatment response to 17 SoC and targeted therapies was monitored, which resulted in drug-dependent inter- and intra-patient specific growth inhibition. Analysis of the molecular data of the models and patient tissue r...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-02-17 | PXD027419 | Pride
Background and Aim: Crohn's disease (CD) and ulcerative colitis (UC) are the two major chronic inflammatory bowel diseases (IBD). Although their symptoms are similar, their pathological features and clinical treatments differ. Currently, distinguishing between these diseases involves invasive proce...
ORGANISM(S): Homo sapiens (Human) 
2025-12-01 | PXD057120 | Pride
This study investigated the effects of fetal fraction (FF) of cell-free fetal DNA on the positive predictive value in non-invasive prenatal testing (NIPT), identified an FF “grey zone” impairing NIPT performance, and developed a predicted model incor
Sort   by:  
 Page size