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ProteomicsHeightened Procoagulation After Post-operative Thromboprophylaxis Completion in Colorectal Cancer Patients with Metastatic Bone Disease
Platelets play a pivotal role in venous thromboembolism (VTE) and in mediating colorectal cancer (CRC) progression. Still, platelets’ role in the hypercoagulability after surgical intervention for metastatic bone diseases (MBD) is ill-defined. Here, we utilised a high-resolution imaging approach to ...
ORGANISM(S): Homo sapiens (Human) 
2023-02-23 | PXD034160 | Pride
Serum Blood Colorectal cancer Proteomics Platelets 
UnknownShort-term high-fat diet intake leads to exacerbation of concanavalin A-induced liver injury through the induction of procoagulation state.
Not available
S-EPMC7021552 | biostudies-literature
UnknownProtonated-chitosan sponge with procoagulation activity for hemostasis in coagulopathy.
Not available
S-EPMC11314896 | biostudies-literature
ProteomicsActivation of Wnt/β-catenin signaling in subchondral bone osteoblast responced to hypoxia lead to osteoarthritis-like phenotype in articular chondrocyte
The crosstalk between the cartilage and subchondral bone plays a crucial role in the pathogenesis and progression of OA. The aim of this study was to identify soluble mediators released by osteoblasts that could induce the release of catabolic factors by chondrocytes. Global protein sequencing of su...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD021135 | Pride
Osteoarthritis(oa)  subchondral bone  articular cartilage  procoagulation  hypoixa  wnt pathway  β-catenin 
GenomicsMechanism of RUNX1 targeted AKT3 regulated alveolar procoagulant fibrinolytic inhibition in ARDS
Acute respiratory distress syndrome (ARDS) is an acute inflammatory lung injury and one of the serious life-threatening forms of respiratory failure. Alveolar procoagulation and fibrinolytic inhibition constitute the core part of the pathophysiology of ARDS, RUNX1 plays an important role in this pat...
ORGANISM(S): Rattus norvegicus 
2024-01-31 | GSE236748 | GEO
UnknownTranscriptome Analysis of Hypothalamic Gene Expression during Daily Torpor in Djungarian Hamsters (Phodopus sungorus).
Not available
S-EPMC5346580 | biostudies-literature
UnknownThe new composition of circulating microvesicles: optimized protocols and reassessment of their characteristics and physiological functions.
Not available
S-EPMC12277571 | biostudies-literature
UnknownPCSK9 as an Atherothrombotic Risk Factor.
Not available
S-EPMC9916735 | biostudies-literature
ProteomicsEffect of MSC and MSC-derived extracellular vesicles on human blood coagulation
Mesenchymal stem cells (MSC) have emerged as potent therapeutic tool for a number of pathologies, including immune ones. However, unwelcome effects of MSC on the blood coagulation were revealed in some cases, which require more in-depth analysis. In this study, we explored the trombotic properties o...
ORGANISM(S): Homo sapiens (Human) 
2019-03-26 | PXD012768 | Pride
Human Mesenchymal stem cells Vesicles 
UnknownThe Toxicology of Native Fucosylated Glycosaminoglycans and the Safety of Their Depolymerized Products as Anticoagulants.
Not available
S-EPMC8467514 | biostudies-literature
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