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ProteomicsMulti-omics biomarker pipeline reveals elevated levels of protein-glutamine gamma-glutamyltransferase 4 in seminal plasma of prostate cancer patients
Prostate-specific antigen, a blood serum biomarker of prostate cancer, lacks specificity and prognostic significance, so considerable efforts are devoted to developing novel biomarkers. Seminal plasma, due to its proximity to prostate, is a promising fluid for biomarker discovery and non-invasive di...
ORGANISM(S): Homo sapiens (Human) 
2019-08-02 | PXD007657 | Pride
Prostate cancer  biomarker discovery  seminal plasma  proteomics  mass spectrometry  selected reaction monitoring  tgm4  protein-glutamine gamma-glutamyltransferase 4 
UnknownMulti-omics Biomarker Pipeline Reveals Elevated Levels of Protein-glutamine Gamma-glutamyltransferase 4 in Seminal Plasma of Prostate Cancer Patients.
Not available
S-EPMC6731075 | biostudies-literature
TranscriptomicsGenome-wide copy number variant analysis in inbred lines of chickens with different susceptibility to MarekM-bM-^@M-^Ys disease
MarekM-bM-^@M-^Ys disease virus (MDV) is an oncovirus causing tumor disease known as MarekM-bM-^@M-^Ys disease (MD) in chicken. Breeding of chickens genetically resistant to MD is considered a vital augment to better control MD. To find the mechanism underlying the genetic resistance to MD, a genomi...
ORGANISM(S): Gallus gallus 
2012-09-01 | E-GEOD-38689 | biostudies-arrayexpress
ProteomicsIdentification of Isopeptides Between Human Tissue Transglutaminase and Wheat, Rye, and Barley Gluten Peptides
Celiac disease (CD) is a chronic immune-mediated enteropathy of the small intestine, which is triggered by the ingestion of storage proteins (gluten) from wheat, rye, and barley in genetically predisposed individuals. Human tissue transglutaminase (TG2) plays a central role in the pathogenesis of CD...
ORGANISM(S): Homo Sapiens Triticum Aestivum Secale Cereale Hordeum Vulgare 
2020-08-27 | PXD017693 | panorama
GenomicsH3K4me3Q5ser ChIP-seq of H3.3 or H3.3Q5A expressing PANC-1 cells and TGM2 knockdown PANC-1 cells
H3K4me3Q5ser ChIP-seq were performed in H3.3 or H3.3Q5A expressing PANC-1 cells and TGM2 knockdown PANC-1 cells to investigate genes directly regulated by H3K4me3Q5ser.
ORGANISM(S): Homo sapiens 
2025-05-08 | E-MTAB-14997 | biostudies-arrayexpress
ProteomicsProteomics analysis of the brain from a Gaucher disease mouse identifies pathological pathways including a possible role for transglutaminase 1
Gaucher disease (GD) is caused by the defective activity of acid beta-glucosidase (GCase) which results from mutations in GBA1. Neurological forms of GD (nGD) can be generated in mice by intra-peritoneal injection of conduritol B-epoxide (CBE) which irreversibly inhibits GCase. Using this approach, ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-07-12 | MSV000092415 | MassIVE
GenomicsGenome-wide copy number variant analysis in inbred lines of chickens with different susceptibility to Marek’s disease
Marek’s disease virus (MDV) is an oncovirus causing tumor disease known as Marek’s disease (MD) in chicken. Breeding of chickens genetically resistant to MD is considered a vital augment to better control MD. To find the mechanism underlying the genetic resistance to MD, a genomic structural variati...
ORGANISM(S): Gallus gallus 
2012-09-01 | GSE38689 | GEO
UnknownCharacterization and Physiological Differences of Two Primary Cultures of Human Normal and Hypertrophic Scar Dermal Fibroblasts: A Pilot Study.
Not available
S-EPMC11504723 | biostudies-literature
MetabolomicsThe in-gel proteomic characterization of exercise-induced sweat - (part III)
Not available
ORGANISM(S): Homo sapiens 
ST001072 | MetabolomicsWorkbench
ProteomicsTCF4 trinucleotide repeat expansion drives distinct proteomic signatures in Fuchs endothelial corneal dystrophy
The aims of this study were to use an isogenic cell model system to investigate the proteomic consequences of TCF4 trinucleotide repeat expansion in Fuchs endothelial corneal dystrophy (FECD) and to identify potential molecular pathways contributing to disease pathogenesis. We used our previously es...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD075094 | Pride
Retina Fuchs endothelial corneal dystrophy (fecd) Ctg repeat 
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