Sort   by:  
 Page size 
MetabolomicsProteolytic-Resistant Self-Assembling Peptide Nanofibers Combat Specific Bacterial Infections via Trap-and-Kill

The rise in global antibiotic resistance highlights the urgent need for effective antimicrobial agents. Antimicrobial peptides (AMPs) offer a potential solution to combat bacterial resistance. However, key challenges remain in addressing the limitations of current peptide drugs and biomaterials, ...

2025-06-13 | MTBLS12424 | MetaboLights
MetabolomicsMetabolite control of enzyme activity links stress to biosynthetic regulation

Cells must continuously adjust metabolic output to maintain homeostasis under changing environmental conditions, yet the mechanisms that enable rapid and reversible control of pathway activity remain largely unknown. The methylerythritol phosphate (MEP) pathway, of bacterial origin and conserved ...

2026-02-04 | MTBLS12456 | MetaboLights
MetabolomicsCommensal intestinal microbiota regulates host luminal proteolytic activity and intestinal barrier integrity through β-glucuronidase activity
Not available
ORGANISM(S): Homo sapiens 
ST001718 | MetabolomicsWorkbench
MetabolomicsCommensal intestinal microbiota regulates host luminal proteolytic activity and intestinal barrier integrity through β-glucuronidase activity (Part 2)
Not available
ORGANISM(S): Mus musculus 
ST002090 | MetabolomicsWorkbench
MetabolomicsA Bidirectional Regulatory ACLY-NLRP3 Axis Integrates Metabolic and Inflammatory Signaling to Control NLRP3 Inflammasome Activation

The NLRP3 inflammasome is critical for host defense against bacterial infection and is involved in the pathogenesis of various inflammatory diseases. The aggregation of its sensor protein NLRP3 is a pivotal checkpoint for inflammasome activation. Howev...

2026-01-07 | MTBLS13400 | MetaboLights
GenomicsAmoeboid-Mesenchymal Transition and the Proteolytic Control of Cancer Invasion Plasticity [RNA-Seq]
Amoeboid-Mesenchymal Transition and the Proteolytic Control of Cancer Invasion Plasticity [RNA-Seq]
PRJNA1380335 | ENA
GenomicsAmoeboid-Mesenchymal Transition and the Proteolytic Control of Cancer Invasion Plasticity [scRNA-seq]
Amoeboid-Mesenchymal Transition and the Proteolytic Control of Cancer Invasion Plasticity [scRNA-seq]
PRJNA1380334 | ENA
TranscriptomicsADAM13 knockdown in Xenopus laevis cranial neural crest
ADAMs are transmembrane metalloproteases that control cell behavior by cleaving both cell adhesion and signaling molecules. The cytoplasmic domain of ADAMs can regulate the proteolytic activity by controlling the subcellular localization and/or the activation of the protease domain. Here we show tha...
ORGANISM(S): Xenopus laevis 
2011-02-22 | E-GEOD-21517 | biostudies-arrayexpress
ProteomicsProteolytic Cleavage Activates the Mitochondrial Isoform of TOP3A
The TOP3A gene encodes two isoforms, one targeted to the nucleus and one to mitochondria. Nuclear TOP3A functions as part of the BTRR complex to resolve double Holliday junctions during homologous recombination, while the mitochondrial isoform separates hemicatenated daughter mitochondrial DNA molec...
ORGANISM(S): Homo sapiens (Human) 
2025-10-01 | PXD064926 | Pride
Top3a Mitochondria Mitochondrial processing peptidase (mmp) Proteolytic cleavage product 
UnknownNeutrophils and Activated Macrophages Control Mucosal Immunity by Proteolytic Cleavage of Antileukoproteinase.
Not available
S-EPMC5985294 | biostudies-literature
Sort   by:  
 Page size