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TranscriptomicsKnockout of Pseudouridine synthase 1 (PUS1) in mice. [Kidney]
In an effort to produce a mouse model of Mitochondrial Myopathy with Lactic acidosis and Sideroblastic Anemia (MLASA), we knocked out the gene for Pseudouridine synthase 1 (PUS1), an enzyme that modifies uridine to pseudouridine in many cytoplasmic and mitochondrial tRNAs, as well as other cellular ...
ORGANISM(S): Mus musculus 
2016-05-16 | E-GEOD-77819 | biostudies-arrayexpress
TranscriptomicsKnockout of Pseudouridine synthase 1 (PUS1) in mice. [Liver]
In an effort to produce a mouse model of Mitochondrial Myopathy with Lactic acidosis and Sideroblastic Anemia (MLASA), we knocked out the gene for Pseudouridine synthase 1 (PUS1), an enzyme that modifies uridine to pseudouridine in many cytoplasmic and mitochondrial tRNAs, as well as other cellular ...
ORGANISM(S): Mus musculus 
2016-05-16 | E-GEOD-77820 | biostudies-arrayexpress
TranscriptomicsKnockout of Pseudouridine synthase 1 (PUS1) in mice. [Brain]
In an effort to produce a mouse model of Mitochondrial Myopathy with Lactic acidosis and Sideroblastic Anemia (MLASA), we knocked out the gene for Pseudouridine synthase 1 (PUS1), an enzyme that modifies uridine to pseudouridine in many cytoplasmic and mitochondrial tRNAs, as well as other cellular ...
ORGANISM(S): Mus musculus 
2016-05-16 | E-GEOD-77817 | biostudies-arrayexpress
TranscriptomicsKnockout of Pseudouridine synthase 1 (PUS1) in mice. [Heart]
In an effort to produce a mouse model of Mitochondrial Myopathy with Lactic acidosis and Sideroblastic Anemia (MLASA), we knocked out the gene for Pseudouridine synthase 1 (PUS1), an enzyme that modifies uridine to pseudouridine in many cytoplasmic and mitochondrial tRNAs, as well as other cellular ...
ORGANISM(S): Mus musculus 
2016-05-16 | E-GEOD-77818 | biostudies-arrayexpress
TranscriptomicsKnockout of Pseudouridine synthase 1 (PUS1) in mice. [M1-Muscle]
In an effort to produce a mouse model of Mitochondrial Myopathy with Lactic acidosis and Sideroblastic Anemia (MLASA), we knocked out the gene for Pseudouridine synthase 1 (PUS1), an enzyme that modifies uridine to pseudouridine in many cytoplasmic and mitochondrial tRNAs, as well as other cellular ...
ORGANISM(S): Mus musculus 
2016-05-16 | E-GEOD-77821 | biostudies-arrayexpress
TranscriptomicsKnockout of Pseudouridine synthase 1 (PUS1) in mice. [M2-Muscle]
In an effort to produce a mouse model of Mitochondrial Myopathy with Lactic acidosis and Sideroblastic Anemia (MLASA), we knocked out the gene for Pseudouridine synthase 1 (PUS1), an enzyme that modifies uridine to pseudouridine in many cytoplasmic and mitochondrial tRNAs, as well as other cellular ...
ORGANISM(S): Mus musculus 
2016-05-16 | E-GEOD-77822 | biostudies-arrayexpress
GenomicsPseudouridine in small RNAs
Pseudouridine in small RNAs
PRJNA958093 | ENA
GenomicsPseudouridine modification detection in mRNA
Pseudouridine modification detection in mRNA
PRJEB56934 | ENA
ProteomicsPUS7 cytoplasmic localization directs a pseudouridine-mediated cellular stress response (CU-OOH)
Pseudouridine is an abundant post-transcriptional modification found across all classes of RNA. Since its discovery in mRNAs a decade ago, it has been widely speculated that Y might govern additional post-transcriptional regulation of gene expression. Here, we demonstrate that one of the principal e...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-01-28 | PXD073675 | Pride
Pus7 Localization Stress response Pseudouridine 
GenomicsA comprehensive tRNA pseudouridine map dependent on human stand-alone pseudouridine synthases
A comprehensive tRNA pseudouridine map dependent on human stand-alone pseudouridine synthases
PRJNA1207010 | ENA
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