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Pseudouridine is an abundant post-transcriptional modification found across all classes of RNA. Since its discovery in mRNAs a decade ago, it has been widely speculated that Y might govern additional post-transcriptional regulation of gene expression. Here, we demonstrate that one of the principal e...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-01-28 | PXD073675 | Pride
Pseudouridine (Ψ) is an abundant post-transcriptional modification found across all classes of RNA. Since its discovery in mRNAs a decade ago, it has been widely speculated that Y might govern additional post-transcriptional regulation of gene expression. Here, we demonstrate that one of the princip...
ORGANISM(S): Saccharomyces cerevisiae BY4741 
2026-01-28 | PXD052684 | Pride
Human PUS7 in tRNA pseudouridylation
Expression data from glioblastoma stem cells after knockdown of PUS7
Pseudouridylation of 7SK by PUS7 regulates Pol II transcription elongation
Pseudouridine is the first discovered and the most frequent modification in RNA. However, its biological functions in physiology and human diseases are largely unknown. Here, we show that pseudouridine synthase PUS7 is differentially expressed in glioblastoma patient tissues verse non-tumor brain ti...
ORGANISM(S): Homo sapiens 
2021-06-18 | GSE147342 | GEO
PUS7-Mediated Pseudouridylation of TGFBI Drives Vascular Remodeling in Pulmonary Hypertension
PUS7-Mediated Pseudouridylation of TGFBI Drives Vascular Remodeling in Pulmonary Hypertension
PUS7-Mediated Pseudouridylation of TGFBI Drives Vascular Remodeling in Pulmonary Hypertension II
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