Osteoarthritis (OA) is the most prevalent chronic joint disease that affects a majority of the elderly. Chondrogenic progenitor cells (CPCs) reside in late stage OA cartilage tissue, producing a fibrocartilagenous extra-cellular matrix and can be manipulated in-vitro, to deposit proteins of healthy ...
The goal was to investigate whether the induction of gene expression by vascular endothelial growth factor (VEGF) in endothelial cells depends on endosomal GTPases Rab5A or Rab5C.