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MetabolomicsRed-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Apple extract; UPLC-MS/MS assay)

In this research, we analyzed the effect of oral administration of red-fleshed apple anthocyanin extract (RAAE) on busulfan-treated mice. At first, we showed that the most abundant component in RAAE was cyanidin 3-O-galactoside. To determine the effect of RAAE, mice were divided into control and ...

2021-06-07 | MTBLS2863 | MetaboLights
MetabolomicsRed-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Mouse blood plasma; UPLC-MS/MS assays)

In this research, we analyzed the effect of oral administration of red-fleshed apple anthocyanin extract (RAAE) on busulfan-treated mice. At first, we showed that the most abundant component in RAAE was cyanidin 3-O-galactoside. To determine the effect of RAAE, mice were divided into control and ...

2021-06-07 | MTBLS2782 | MetaboLights
TranscriptomicsHybrid dysfunction and physiological compensation in gene expression
The formation of new species is often a consequence of genetic incompatibilities accumulated between populations during allopatric divergence. When divergent taxa interbreed, these incompatibilities impact physiology and have a direct cost resulting in reduced hybrid fitness. Recent surveys of gene ...
ORGANISM(S): Tigriopus californicus 
2015-01-05 | E-GEOD-62672 | biostudies-arrayexpress
ProteomicsComparative proteomic analysis of gonadal tissue in Solea senegalensis reveals reproductive deregulation associated with F1 individuals
Reproductive dysfunction in captive-bred Senegalese sole (Solea senegalensis) limits the consolidation of its aquaculture production, particularly due to reduced fertility and poor sperm quality in F1 males. To elucidate the molecular mechanisms underlying this problem, a quantitative proteomic anal...
ORGANISM(S): Solea senegalensis 
2026-08-24 | PXD071796 | Pride
Solea senegalensis  gonadal tissue  proteomic analysis  reproductive dysfunction. 
ProteomicsAstral-DIA Proteomics Deciphers the Molecular Landscape of Human Spermatozoa: A Comprehensive Quantitative Proteomic Characterization of Sperm Function and Fertility Potential
Male infertility is fundamentally rooted in developmental defects of germ cells and associated molecular dysregulation, yet the underlying mechanisms remain poorly understood. Data-independent acquisition (DIA) has emerged as a powerful tool in discovery proteomics, enabling the identification of di...
ORGANISM(S): Homo sapiens (Human) 
2025-03-11 | PXD061698 | Pride
Astral-dia  proteomics deciphers  molecular landscape 
ProteomicsAstral-DIA Proteomics Deciphers the Molecular Landscape of Human Spermatozoa: A Comprehensive Quantitative Proteomic Characterization of Sperm Function and Fertility Potential
Male infertility is fundamentally rooted in developmental defects of germ cells and associated molecular dysregulation, yet the underlying mechanisms remain poorly understood. Data-independent acquisition (DIA) has emerged as a powerful tool in discovery proteomics, enabling the identification of di...
ORGANISM(S): Homo sapiens (Human) 
2025-03-10 | PXD061638 | Pride
Astral-dia  proteomics  human spermatozoa  sperm function 
TranscriptomicsTranscription profiling of brains of 10 day old virgin queen, sterile worker, and reproductive worker honey bees
We used microarrays to monitor expression patterns of several thousand genes in the brains of same-aged (10 day old) virgin queens, sterile workers, and reproductive workers in honey bees (Apis mellifera).
ORGANISM(S): Apis mellifera 
2008-07-29 | E-MEXP-1044 | biostudies-arrayexpress
TranscriptomicsMicroarrays reveal oocyte lipid storage droplet gene as key factor in reproductive dysfunction of captive-reared P. monodon
Background: Aquaculture of the black tiger prawn Penaeus monodon remains severely constrained by an almost total dependence on wild-caught broodstock. Reliance on wild-caught broodstock stems, for the most part, from reduced reproductive potential of captive-reared females. Reproductive performance ...
ORGANISM(S): Penaeus monodon 
2011-09-01 | E-GEOD-31862 | biostudies-arrayexpress
TranscriptomicsRequirement for Sun1 in the expression of meiotic reproductive genes and piRNA
The inner nuclear envelope (NE) proteins interact with the nuclear lamina and participate in the architectural compartmentalization of chromosomes. The association of NE proteins with DNA contributes to the spatial rearrangement of chromosomes and their gene expression. Sun1 is an inner nuclear memb...
ORGANISM(S): Mus musculus 
2009-03-11 | E-GEOD-12867 | biostudies-arrayexpress
TranscriptomicsAn embryonic atrazine exposure results in reproductive dysfunction in adult zebrafish and morphological alterations in their offspring
The herbicide atrazine, a suspected endocrine disrupting chemical (EDC), frequently contaminates potable water supplies. Studies suggest alterations in the neuroendocrine system along the hypothalamus-pituitary-gonadal axis; however, most studies address either developmental, pubertal, or adulthood ...
ORGANISM(S): Danio rerio 
2016-03-02 | E-GEOD-73740 | biostudies-arrayexpress
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