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ProteomicsEpidermal Stratification Requires Retromer-Mediated Desmoglein-1 Recycling
Sorting transmembrane cargo is essential for tissue development and homeostasis. However, mechanisms of intracellular trafficking in stratified epidermis are poorly understood. Here we identify an interaction between the retromer endosomal trafficking component, VPS35, and the desmosomal cadherin, D...
ORGANISM(S): Homo sapiens (Human) 
2023-07-24 | PXD036646 | Pride
Desmosome  keratinocyte  epidermal differentiation  skin disease  endosomal trafficking  retromer chaperone  vps35  sam syndrome  cadherin  dsg1  glut1  bioid 
UnknownEpidermal stratification requires retromer-mediated desmoglein-1 recycling.
Not available
S-EPMC9973369 | biostudies-literature
UnknownDe novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Not available
S-EPMC8635440 | biostudies-literature
UnknownRegulation of endosomal clathrin and retromer-mediated endosome to Golgi retrograde transport by the J-domain protein RME-8.
Not available
S-EPMC2776105 | biostudies-literature
UnknownA pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles.
Not available
S-EPMC6975032 | biostudies-literature
Unknownγ-Secretase promotes membrane insertion of the human papillomavirus L2 capsid protein during virus infection.
Not available
S-EPMC6168257 | biostudies-literature
UnknownMutagenesis and structural modeling implicate RME-8 IWN domains as conformational control points.
Not available
S-EPMC9642905 | biostudies-literature
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