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TranscriptomicsFibronectin regulates Wnt7a signaling and satellite cell expansion
The influence of the extracellular matrix (ECM) within the stem cell niche remains poorly understood. We found that Syndecan-4 (Sdc4) and Frizzled-7 (Fzd7) form a coreceptor complex in satellite cells and that binding of the ECM glycoprotein Fibronectin (FN) to Sdc4 stimulates the ability of Wnt7a t...
ORGANISM(S): Mus musculus 
2014-07-11 | E-GEOD-59272 | biostudies-arrayexpress
TranscriptomicsRNA-seq from myogenic satellite cells from a translational porcine model for Duchenne muscular dystrophy, heterozygous female carriers, and their healthy wild-type counterpart
Satellite cells (SCs), the stem cell population of skeletal muscle, are crucial for growth and regeneration, and their dysfunction is increasingly recognized as a contributing factor to Duchenne muscular dystrophy (DMD). DMD is a severe, X-linked disorder caused by DMD gene mutations, leading to lo...
ORGANISM(S): Sus scrofa 
2025-12-11 | E-MTAB-16179 | biostudies-arrayexpress
TranscriptomicsRNA-Sequencing of primary myoblasts from mice with a satellite cell specific knockout of the histone demthylase UTX/KDM6A
The KDM6 histone demethylases (UTX/KDM6A and JMJD3/KDM6B) mediate removal of repressive histone H3K27me3 marks to establish transcriptionally permissive chromatin. Loss of UTX in female mice is embryonic lethal. Unexpectedly, male UTX-null mice escape embryonic lethality due to expression of UTY, a ...
ORGANISM(S): Mus musculus 
2016-03-22 | E-GEOD-69968 | biostudies-arrayexpress
GenomicsMeiotic pairing through barcode-like satellite DNA repeats
Meiotic pairing through barcode-like satellite DNA repeats
PRJNA1469082 | ENA
TranscriptomicsExpression data from differentiating primary culture of equine satellite cells (ESC) incubated with gamma-oryzanol (GO)
Transcriptional profiling of gamma-oryzanol-treated (24h) differentiating equine satellite cells (3rd day of differentiation) compared to control GO-untreated cells. Goal was to determine the effects of gamma-oryzanol influence on gene expression in equine satellite cells during in vitro myogenesis ...
ORGANISM(S): Equus caballus 
2016-02-22 | E-GEOD-73730 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of turkey muscle satellite cells transfected with DAP-siRNA during proliferation and differentiation
In this study, we directly compared turkey muscle satellite cell gene expression between satellite cells with the gene Death-Associated Protein (DAP) knocked down by siRNA transfection and those transfected with a lipofectamine control using our 6K Turkey Skeletal Muscle Long Oligo (TSKMLO) microarr...
ORGANISM(S): Meleagris gallopavo 
2012-05-31 | E-GEOD-35660 | biostudies-arrayexpress
TranscriptomicsNotch signaling/MyoD double deficient embryonic muscle progenitors
Skeletal muscle growth and regeneration rely on myogenic progenitor and satellite cells, the stem cells of postnatal muscle. Elimination of Notch signals during mouse development results in premature differentiation of myogenic progenitors and formation of very small muscle groups. Here we show that...
ORGANISM(S): Mus musculus 
2012-12-31 | E-GEOD-39379 | biostudies-arrayexpress
GenomicsPHF6 drives satellite DNA chromatin remodeling for resolution of replicative stress-induced DNA damage
PHF6 drives satellite DNA chromatin remodeling for resolution of replicative stress-induced DNA damage
PRJNA638912 | ENA
GenomicsGenome-wide mapping of cytosine methylation revealed dynamic DNA methylation patterns associated with rice centromeres
Specification and propagation of the centromeres of eukaryotic chromosomes is determined by epigenetic mechanisms. Unfortunately, the epigenetic characteristics of centromeric DNA and chromatin are difficult to define because the centromeres are composed of highly repetitive DNA sequences in most eu...
ORGANISM(S): Oryza sativa 
2010-04-22 | E-GEOD-21414 | biostudies-arrayexpress
TranscriptomicsExpression data from skeletal muscle satellite cells at different development stages
Satellite cells are responsible for the long-term regenerative capacity of adult skeletal muscle. The diminished muscle performance and regenerative capacity of aged muscle is thought to reflect progressive fibrosis and atrophy. Whether this reduction in muscle competency also involves a diminishmen...
ORGANISM(S): Mus musculus 
2014-05-26 | E-GEOD-47401 | biostudies-arrayexpress
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