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ProteomicsProteomic and biological analysis of metformin senomorphics effects on the mesenchymal stromal cells
Senotherapeutics are new drugs, which can modulate senescence phenomena within tissues and reduces the onset of age-related pathologies. Senotherapeutics are divided in senolytics and senomorphics. The senolytics kill selectively senescent cells, while the senomorphics may delay or block the onset o...
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD028349 | Pride
Mesenchymal stromal cells  senescence  senolytics  senomorphics 
UnknownProteomic and Biological Analysis of the Effects of Metformin Senomorphics on the Mesenchymal Stromal Cells.
Not available
S-EPMC8524175 | biostudies-literature
UnknownNutritional senolytics and senomorphics: Implications to immune cells metabolism and aging - from theory to practice.
Not available
S-EPMC9493043 | biostudies-literature
UnknownSenolytics and Senomorphics Targeting p38MAPK/NF-κB Pathway Protect Endothelial Cells from Oxidative Stress-Mediated Premature Senescence.
Not available
S-EPMC11311971 | biostudies-literature
UnknownCaffeic Acid Acts as a Potent Senomorphic and Alleviates Inflammation and Lung Fibrosis by Covalently Targeting Annexin A5 Protein in Mice.
Not available
S-EPMC12752563 | biostudies-literature
UnknownSenotherapeutics: emerging strategy for healthy aging and age-related disease.
Not available
S-EPMC6386227 | biostudies-literature
UnknownSynergistic ROS Reduction Through the Co-Inhibition of BRAF and p38 MAPK Ameliorates Senescence.
Not available
S-EPMC11672831 | biostudies-literature
UnknownMitigating Pro-Inflammatory SASP and DAMP With Urolithin A: A Novel Senomorphic Strategy.
Not available
S-EPMC12608089 | biostudies-literature
UnknownSenolytics: Eliminating Senescent Cells and Alleviating Intervertebral Disc Degeneration.
Not available
S-EPMC8924288 | biostudies-literature
TranscriptomicsFucoidans are senotherapeutics that enhance SIRT6-Dependent DNA repair
Aging is marked by the accumulation of senescent cells (SnCs), which contribute to tissue dysfunction and age-related diseases. Senotherapeutics, including senolytics which specifically induce lysis of SnCs and senomorphics, which suppress the senescence phenotype, represent promising therapeutic in...
ORGANISM(S): Mus musculus 
2026-05-25 | GSE298234 | GEO
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