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TranscriptomicsQuality control of spliced mRNAs requires the shuttling SR-proteins Gbp2 and Hrb1
Eukaryotic cells have to prevent the export of unspliced pre-mRNAs until intron removal is completed to avoid the expression of aberrant and potentially harmful proteins. Only mature RNAs associate with the export receptor Mex67 (mammalian TAP) and enter the cytoplasm. The underlying nuclear quality...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-04 | E-GEOD-52808 | biostudies-arrayexpress
ProteomicsRNA-controlled nucleocytoplasmic shuttling of mRNA decay factors regulates mRNA synthesis and a novel mRNA decay pathway
mRNA level is controlled by factors that mediate both mRNA synthesis and decay, including the 5’ to 3’ exonuclease Xrn1 - a major mRNA synthesis and decay factor. Here we show that nucleocytoplasmic shuttling of several mRNA decay factors plays a key role in determining both mRNA synthesis and decay...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-09-19 | PXD036414 | Pride
Nucleocytoplasmic shuttling Xrn1 Mrna decay 
TranscriptomicsQuality control of spliced mRNAs requires the shuttling SR-proteins Gbp2 and Hrb1
Eukaryotic cells have to prevent the export of unspliced pre-mRNAs until intron removal is completed to avoid the expression of aberrant and potentially harmful proteins. Only mature RNAs associate with the export receptor Mex67 (mammalian TAP) and enter the cytoplasm. The underlying nuclear quality...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-04 | GSE52808 | GEO
TranscriptomicsThe shuttling SR-like proteins Gbp2 and Hrb1 mediate the nuclear export of spliced mRNAs
Three shuttling SR-like proteins exist in Saccharomyces cerevisiae, Npl3, Gbp2 and Hrb1, that are involved in the nuclear export of mRNAs. In a screen for genes that regulate the export of Gbp2, we identified novel mutants of the splicing factors PRP8 and PRP17 that lead to severe mislocalization de...
ORGANISM(S): Saccharomyces cerevisiae 
2013-08-30 | E-GEOD-20738 | biostudies-arrayexpress
UnknownReconstitution of morphogen shuttling circuits.
Not available
S-EPMC10337948 | biostudies-literature
GenomicsSaccharomyces cerevisiae
Quality control of spliced mRNAs requires the shuttling SR-proteins Gbp2 and Hrb1
PRJNA230517 | ENA
GenomicsBBS6 regulates gene expression via involvement in DNMT1 shuttling
BBS6 regulates gene expression via involvement in DNMT1 shuttling
PRJEB121503 | ENA
GenomicsTAX1BP3 is a SUMOylated Nucleocytoplasmic Shuttling Protein and Protects Against Vascular Neointimal Hyperplasia
TAX1BP3 is a SUMOylated Nucleocytoplasmic Shuttling Protein and Protects Against Vascular Neointimal Hyperplasia
PRJNA1265121 | ENA
UnknownIdentification and partial characterization of new cell density-dependent nucleocytoplasmic shuttling proteins and open chromatin.
Not available
S-EPMC10709462 | biostudies-literature
UnknownNucleocytoplasmic shuttling of the Golgi phosphatidylinositol 4-kinase Pik1 is regulated by 14-3-3 proteins and coordinates Golgi function with cell growth.
Not available
S-EPMC2262966 | biostudies-literature
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