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TranscriptomicsWhole blood transcriptional profiles of patients with active tuberculosis (TB) and other inflammatory and infectious diseases
Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis (M. tuberculosis), is a major cause of morbidity and mortality worldwide and efforts to control TB are hampered by difficulties with diagnosis, prevention and treatment. Most people infected with M. tuberculosis remain asymptomat...
ORGANISM(S): Homo sapiens 
2010-08-11 | E-GEOD-22098 | biostudies-arrayexpress
ProteomicsGlobal Phosphoproteomics Reveals Molecular Networks in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a systemic and heterogeneous autoimmune disease for which its treatment and phosphorylation-dependent regulatory mechanism remain elusive. Here, we aim to explore the molecular mechanism of phosphorylation regulation for SLE. We employed high-throughput Phosphop...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD025559 | Pride
Phosproteomics  sle remission stage  sle active stage  kinases  parallel reaction monitoring 
ProteomicsGlobal Phosphoproteomics Reveals Molecular Networks in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a systemic and heterogeneous autoimmune disease for which its treatment and phosphorylation-dependent regulatory mechanism remain elusive. Here, we aim to explore the molecular mechanism of phosphorylation regulation for SLE. We employed high-throughput Phosphop...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD025399 | Pride
Phosproteomics  sle remission stage  sle active stage  kinases  parallel reaction monitoring 
ProteomicsGlobal Phosphoproteomics Reveals Molecular Networks in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a systemic and heterogeneous autoimmune disease for which its treatment and phosphorylation-dependent regulatory mechanism remain elusive. Here, we aim to explore the molecular mechanism of phosphorylation regulation for SLE. We employed high-throughput Phosphop...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD025076 | Pride
Phosproteomics  sle remission stage  sle active stage  kinases  parallel reaction monitoring 
TranscriptomicsModular repertoire analyses identify dynamic type I and type II interferon transcriptional signatures in adult SLE patients
Gene expression profiling (compared to healthy controls) to identify patients with active SLE disease and patients with quiescent disease 157 “SLE” and 20 “Healthy controls of SLE were followed up for up to 3 years. Clinical assessment, current treatment, laboratory results and SLEDAI score were col...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-49454 | biostudies-arrayexpress
MetabolomicsComparative 1H-NMR Lipoprotein Profiling of Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients Highlights Disease-Specific Lipoprotein Dysregulation

Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are systemic autoimmune diseases associated with increased cardiovascular risk and metabolic alterations. We applied 1H-NMR spectroscopy to profile lipoproteins and metabolites in women with RA, SLE, and healthy controls. Both RA an...

2026-02-02 | MTBLS13820 | MetaboLights
TranscriptomicsBlood Transcriptional Profiles in Human Active and Latent Tuberculosis
This series regroups different datasets (training set, test set, validation set, longitudinal set, separated cell set) to identify and characterise a specific transcriptional signature for patients with active TB, distinct from patients with latent TB and healthy controls. The training set dataset w...
ORGANISM(S): Homo sapiens 
2010-08-11 | E-GEOD-19491 | biostudies-arrayexpress
UnknownDomains for inclusion in a novel Treatment Response Measure for Systemic Lupus Erythematosus (TRM-SLE): results of a modified Delphi study.
Not available
S-EPMC12067843 | biostudies-literature
TranscriptomicsExpression data from lupus NZB/W, NZM2410, NZW/BXSB mouse kidneys prenephritic and nephritic.
Nephritis (LN) is a serious manifestation of SLE. Therapeutic studies in mouse LN models do not always predict outcomes of human therapeutic trials, raising concerns about the human relevance of these models. In this study we used an unbiased transcriptional network approach to define similarities a...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-32583 | biostudies-arrayexpress
TranscriptomicsRNA-seq of CD56+ NK cells from juvenile systemic lupus erythematosus (JSLE) patients and healthy controls
Transcriptional profiling of peripheral blood CD56+ natural killer cells from active JSLE patients, patients with low disease activity and healthy controls.
ORGANISM(S): Homo sapiens 
2024-06-07 | E-MTAB-13422 | biostudies-arrayexpress
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