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ProteomicsDesign of a proteolytically stable sodium-calcium exchanger 1 (NCX1)-phospholemman (PLM) disruptor peptide for in vivo studies
The cardiac sodium–calcium exchanger (NCX1) is important for normal Na+ and Ca2+ homeostasis and cardiomyocyte relaxation and contraction. NCX1 activity is reduced by its endogenous inhibitor phosphorylated phospholemman (pSer68-PLM). Disrupting the pSer68-PLM-NCX1 interaction is therefore a potenti...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD022797 | Pride
Phospholemman  sodium-calcium exchanger  peptidomimetics  peptide array  cardiac 
GenomicsThe role of stretch, tachycardia and sodium-calcium exchanger in induction of early cardiac remodeling
The role of stretch, tachycardia and sodium-calcium exchanger in induction of early cardiac remodeling
PRJNA557667 | ENA
ProteomicsNCLX proximity biotinylation screen
The mitochondrial sodium/calcium exchanger, NCLX, is critical to maintaining mitochondrial calcium homeostasis, yet little remains known about the mechanisms regulating its function. Here, we performed proximity biotinylation screening to identify the NCLX interactome and potential protein regulator...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000093004 | MassIVE
TranscriptomicsThe role of stretch, tachycardia and sodium-calcium exchanger in induction of early cardiac remodeling
Accute stretch and tachycardia are capable of inducing pathological excitation transcription coupling - an early invent before structural cardiac remodeling which transitions to heart failure. The sodium calcium exchanger is a key player in maintaining calcium homeostasis and is implicated in pathol...
ORGANISM(S): Rattus norvegicus 
2020-08-12 | GSE135172 | GEO
UnknownIntegrin-mediated membrane blebbing is dependent on sodium-proton exchanger 1 and sodium-calcium exchanger 1 activity.
Not available
S-EPMC3323054 | biostudies-literature
UnknownCloning and characterization of a potassium-dependent sodium/calcium exchanger in Drosophila.
Not available
S-EPMC2151195 | biostudies-literature
UnknownBlockade of sodium‑calcium exchanger via ORM-10962 attenuates cardiac alternans.
Not available
S-EPMC8035081 | biostudies-literature
UnknownSodium-Calcium Exchanger Can Account for Regenerative Ca2+ Entry in Thin Astrocyte Processes.
Not available
S-EPMC6102320 | biostudies-literature
UnknownExpression of the sodium/calcium/potassium exchanger, NCKX4, in ameloblasts.
Not available
S-EPMC3535175 | biostudies-literature
UnknownStructural insight into the allosteric inhibition of human sodium-calcium exchanger NCX1 by XIP and SEA0400.
Not available
S-EPMC10897212 | biostudies-literature
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