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Mice lacking the zinc finger transcription factor Specificity protein 3 (Sp3) die prenatally in the C57Bl/6 background. To elucidate the cause of mortality we analyzed the potential role of Sp3 in embryonic heart development. Sp3 null hearts display defective looping at E10.5, and at E14.5 the Sp3 n...
ORGANISM(S): Mus musculus 
In this study, we developed a complete, robust, and simple sample preparation workflow named PEPPI-SP3 for top-down proteomics by combining PEPPI-MS with the magnetic bead-based protein purification approach used in SP3 (single-pot, solid-phase-enhanced sample preparation), now one of the standard s...
ORGANISM(S): Homo Sapiens (human) 
Streptococcus pyogenes SP3-LAU Genome sequencing and assembly
Genome sequencing and assembly of Halocella sp. SP3-1
Investigation of the binding behaviour of Sp1, Sp2, Sp3 and NF-ya, NF-yb and NF-yc in mouse embryonic fibroblasts and of Sp1, Sp2 and Sp3 in HEK-293 cells reveals distinct binding of the seemingly similar transcription factors Sp1/3 and Sp2.
ORGANISM(S): Mus musculus 
Neocallimastix lanati sp3 Transcriptome - S3_RNA_MC_RCG
Neocallimastix lanati sp3 Transcriptome - Cellobiose_RNA_MC_1
Neocallimastix lanati sp3 Transcriptome - Filterpaper_RNA_MC_2
Neocallimastix lanati sp3 Transcriptome - RCG_RNA_MC_1
Neocallimastix lanati sp3 Transcriptome - Cellobiose_RNA_MC_2
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