Sort   by:  
 Page size 
TranscriptomicsThe Mot1 ATPase and Spt16 Histone Chaperone Cooperatively Regulate Transcription
Mot1 is a conserved and essential Swi2/Snf2 ATPase that can remove TATA-binding protein (TBP) from DNA using ATP hydrolysis, and in so doing exerts global effects on transcription. Spt16 is also essential and functions globally in transcriptional regulation as a component of the FACT histone chaper...
ORGANISM(S): Saccharomyces cerevisiae 
2016-05-16 | E-GEOD-72117 | biostudies-arrayexpress
GenomicsGenome-wide Localization of Mot1, Spt16, and Nucleosomes in mot1, spt16, and mot1 spt16 cells
Mot1 is a conserved and essential Swi2/Snf2 ATPase that can remove TATA-binding protein (TBP) from DNA using ATP hydrolysis, and in so doing exerts global effects on transcription. Spt16 is also essential and functions globally in transcriptional regulation as a component of the FACT histone chaper...
ORGANISM(S): Saccharomyces cerevisiae 
2016-05-16 | E-GEOD-80234 | biostudies-arrayexpress
ProteomicsN-terminus of Spt16 anchors FACT to Mcm2 for parental histone recycling
Parental histone recycling is essential for the restoration of chromatin-based epigenetic information during chromatin replication; however, the specific mechanisms underlying the local recycling of parental histones remain poorly understood. Here, we reveal an unexpected role of the Spt16-N domain ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-01-26 | PXD043392 | Pride
Mcm2-7 Fact，parental histone recycling 
GenomicsGenome-wide Localization of Mot1, Spt16, and Nucleosomes in mot1, spt16, and mot1 spt16 cells
Mot1 is a conserved and essential Swi2/Snf2 ATPase that can remove TATA-binding protein (TBP) from DNA using ATP hydrolysis, and in so doing exerts global effects on transcription. Spt16 is also essential and functions globally in transcriptional regulation as a component of the FACT histone chapero...
ORGANISM(S): Saccharomyces cerevisiae 
2016-05-16 | GSE80234 | GEO
ProteomicsPhosphorylation of the FACT histone chaperone subunit SPT16 modulates Arabidopsis development and affects chromatin at RNA polymerase II transcriptional start sites
The heterodimeric histone chaperone FACT consisting of SSRP1 and SPT16 contributes to dynamic nucleosome rearrangements during various DNA-dependent processes including transcription. In search of post-translational modifications that may regulate the activity of FACT, SSRP1 and SPT16 were isolated ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-06-09 | PXD028534 | Pride
Arabidopsis Fact complex Acetylation Phosphorylation 
UnknownProteasomal Regulation of Mammalian SPT16 in Controlling Transcription.
Not available
S-EPMC8088127 | biostudies-literature
UnknownMutant versions of the S. cerevisiae transcription elongation factor Spt16 define regions of Spt16 that functionally interact with histone H3.
Not available
S-EPMC3108975 | biostudies-literature
TranscriptomicsThe Mot1 ATPase and Spt16 Histone Chaperone Cooperatively Regulate Transcription
Mot1 is a conserved and essential Swi2/Snf2 ATPase that can remove TATA-binding protein (TBP) from DNA using ATP hydrolysis, and in so doing exerts global effects on transcription. Spt16 is also essential and functions globally in transcriptional regulation as a component of the FACT histone chapero...
ORGANISM(S): Saccharomyces cerevisiae 
2016-05-16 | GSE72117 | GEO
UnknownStructure of the human histone chaperone FACT Spt16 N-terminal domain.
Not available
S-EPMC4741192 | biostudies-literature
TranscriptomicsGenomic Run On (GRO): determination of the nascent transcriptional rates in a spt16 mutant
We analyzed the effect of SPT16 on the transcription rates, mRNA stabilities and mRNA levels by doing GRO experiments in a thermosensitive spt16 point mutant (G132D) mutant at 35 ºC comparing with permisive temperature (30 ºC) and a wt treated in the same way. Cells (wt or spt16 mutant) were grown...
ORGANISM(S): Saccharomyces cerevisiae 
2016-01-05 | E-GEOD-64006 | biostudies-arrayexpress
Sort   by:  
 Page size