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ProteomicsSCI1 co-purifies with the STRIPAK protein PRO11
The STRIPAK complex is a conserved multi-protein complex, which is found in animals and in fungi but not in prokaryotes and plants. It is involved in growth and development, regulating signal transduction in cellular pathways, for example hippo and MAPK, and it has a role in human neuronal diseases,...
ORGANISM(S): Sordaria macrospora k-hell 
2018-08-21 | PXD008959 | Pride
Stripak Fruiting-body development Sci1 Pro11 Hyphal fusion Sordaria macrospora 
GenomicsSTRIPAK directs PP2A activity to promote oncogenic transformation
STRIPAK directs PP2A activity to promote oncogenic transformation
PRJNA485011 | ENA
TranscriptomicsSTRIPAK directs PP2A activity to promote oncogenic transformation
We evaluated the effects of suppressing MAP4K4 on transcriptome and YAP1 pathway based on the observation that partial suppression of MAP4K4 leads to transformation through activation of YAP1. Mutations and deletions involving subunits of the serine-threonine phosphatase PP2A occur in a broad range ...
ORGANISM(S): Homo sapiens 
2019-12-01 | GSE118272 | GEO
GenomicsThe STRIPAK complex regulates response to chemotherapy through p21 and p27
The STRIPAK complex regulates response to chemotherapy through p21 and p27
PRJNA607753 | ENA
ProteomicsA. nidulans STRIPAK - Assembly of a heptameric STRIPAK complex is required for coordination of light-dependent multicellular fungal development with secondary metabolism in Aspergillus nidulans
Eukaryotic striatin forms striatin-interacting phosphatase and kinase (STRIPAK) complexes that control many cellular processes including development, cellular transport, signal transduction, stem cell differentiation and cardiac functions. However, detailed knowledge of complex assembly and its role...
ORGANISM(S): Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) 
2019-03-12 | PXD011927 | Pride
A. nidulans Lc-msms 
UnknownSTK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism.
Not available
S-EPMC7182433 | biostudies-literature
UnknownThe Dysregulation and Prognostic Analysis of STRIPAK Complex Across Cancers.
Not available
S-EPMC7365848 | biostudies-literature
ProteomicsThe STRIPAK dependent phosphorylation of distinct residues of GUL1 controls hyphal morphology and sexual fertility
STRIPAK is a highly conserved eukaryotic signalling complex controlling a wide range of developmental processes in microorganisms as well as humans. This study uses iTRAQ-based proteomic and phosphoproteomic analyses to expand the identification of differentially phosphorylated proteins, comparing t...
ORGANISM(S): Sordaria macrospora 
2020-09-30 | PXD016296 | Pride
Phosphoproteomics Stripak Sordaria macrospora Itraq Lc-msms 
ProteomicsThe STRIPAK signaling complex regulates dephosphorylation of GUL1, an RNA-binding protein that shuttles on endosomes
STRIPAK is a highly conserved eukaryotic signalling complex controlling a wide range of developmental processes in microorganisms as well as humans. This study uses iTRAQ-based proteomic and phosphoproteomic analyses to expand the identification of differentially phosphorylated proteins, comparing t...
ORGANISM(S): Sordaria macrospora k-hell 
2020-09-24 | PXD021646 | Pride
Lc-msms Phosphoproteomics Sordaria macrospora Itraq 
UnknownCryo-EM structure of the Hippo signaling integrator human STRIPAK.
Not available
S-EPMC8315899 | biostudies-literature
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