Sort   by:  
 Page size 
MetabolomicsAutomated, Parallel Mass Spectrometry Imaging and Structural Identification of Lipids
We report a method that enables automated data-dependent acquisition of lipid tandem mass spectrometry data in parallel with a high-resolution mass spectrometry imaging experiment. The method does not increase the total image acquisition time and is combined with automatic structural assignment. Thi...
2018-05-21 | MTBLS597 | MetaboLights
MetabolomicsMultiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health

In order to explore opportunities for personalized and predictive health care, we collected serial clinical measurements, health surveys and multiomics profiles (genomics, proteomics, autoantibodies, metabolomics and gut microbiome) from 96 individuals. The participants underwent data-driven heal...

2021-09-02 | MTBLS2187 | MetaboLights
MetabolomicsIlluminating the dark space of neutral glycosphingolipidome by selective enrichment and profiling at multi-structural levels

Glycosphingolipids (GSLs) are essential components of cell membranes, particularly enriched in the nervous system. Altered molecular distributions of GSLs are increasingly associated with human diseases, emphasizing the significance of lipidomic profiling. Traditional GSL analysis methods are ham...

2024-06-25 | MTBLS10400 | MetaboLights
TranscriptomicsStructural systems biology evaluation of metabolic thermotolerance in Escherichia coli
Investigation of whole genome gene expression level in E. coli K-12 MG1655 in glucose M9 minimal media with/without heatshock A six chip study using total RNA recovered from E. coli K-12 MG1655 grown up to OD600nm 0.6 (mid-exponential phase) in M9 minimal media supplemented with 0.2% glucose with/wi...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2013-06-20 | E-GEOD-42675 | biostudies-arrayexpress
TranscriptomicsMapping DNA structural variation in dogs
DNA structural variation (SV) comprises a major portion of genetic diversity, but its biological impact is unclear. We propose that the genetic history and extraordinary phenotypic variation of dogs make them an ideal mammal in which to study the effects of SV on biology and disease. The hundreds of...
ORGANISM(S): Canis lupus familiaris 
2010-05-22 | E-GEOD-18317 | biostudies-arrayexpress
ProteomicsProtein complexes in cells by AI-assisted structural proteomics (Proteomics)
Accurately modeling the structures of proteins and their complexes using artificial intelligence is revolutionizing molecular biology. Experimental data enable a candidate-based approach to systematically model novel protein assemblies. Here, we use a combination of in-cell crosslinking mass spectro...
ORGANISM(S): Bacillus Subtilis Subsp. Subtilis Str. 168 
2023-02-16 | PXD035521 | JPOST Repository
ProteomicsProtein complexes in cells by AI-assisted structural proteomics (Cofractionation MS)
Accurately modeling the structures of proteins and their complexes using artificial intelligence is revolutionizing molecular biology. Experimental data enable a candidate-based approach to systematically model novel protein assemblies. Here, we use a combination of in-cell crosslinking mass spectro...
ORGANISM(S): Bacillus Subtilis Subsp. Subtilis Str. 168 
2023-02-16 | PXD035520 | JPOST Repository
UnknownA structural biology perspective on NMDA receptor pharmacology and function.
Not available
S-EPMC4641752 | biostudies-literature
UnknownA structural biology community assessment of AlphaFold2 applications.
Not available
S-EPMC9663297 | biostudies-literature
UnknownHS-AFM single-molecule structural biology uncovers basis of transporter wanderlust kinetics.
Not available
S-EPMC11490224 | biostudies-literature
Sort   by:  
 Page size