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Modelling Approach

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1Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, USA 2Institute for Quantitative and Computational Biosciences, University of California, Los Angeles, Los Angeles, CA, USA 3Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, USA (1)

IsPrivate

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Modification

4x(15)N labeled L-arginine (1)

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pSILAC method coupled with two complementary digestion approaches reveals PRPF39 as a new E7070-dependent DCAF15 substrate

In this study, we used a novel strategy of pSILAC method coupled with two complementary digestion approaches to find potential substrates of E7070, and reveals PRPF39 as E7070-dependent DCAF15 substrate.

ORGANISM(S): Homo Sapiens

PXD015892 |

Vps10-mediated targeting of Pep4 determines the activity of the vacuole in a substrate-dependent manner.

Not available

S-EPMC6646403 | biostudies-literature

Wnt/β-catenin signaling regulates cardiac Cx43 in a metabolic substrate-dependent manner.

Not available

S-EPMC12519157 | biostudies-literature

Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament

Cyclic dipeptides are produced by organisms across all domains of life, with many exhibiting anticancer and antimicrobial properties. Oxidations are often key to their biological activities, particularly C-C bond oxidation catalyzed by tailoring enzymes including cyclodipeptide oxidases. These flavi...

ORGANISM(S): Nocardiopsis dassonvillei

2025-01-06 | PXD058613 | Pride