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MetabolomicsMelatonin enhances function of porcine immature Sertoli cells via modulating gene expression and metabolism

Melatonin (MT), a neurohormone synthesized and secreted primarily by the pineal gland, is of vital function to animal reproduction. However, the effect of MT treatment on porcine immature Sertoli cells (iSCs) remains unclear. Here, MT treatment (10 nM, 36 h) could elevate mitochondrial function a...

2025-01-06 | MTBLS11126 | MetaboLights
UnknownImproving the safety of cell therapy with the TK-suicide gene.
Not available
S-EPMC4419602 | biostudies-literature
no omics definedTranscription profiling of human CD8 T cells activated with CD3 or CD3-CD28 prior to retroviral transduction and different selection procedures (G418 or NGFR-MACS)n
effect of different T cell activations (CD3 and CD3-CD28) prior retroviral transduction and different selection procedures (G418 or NGFR-MACS)
ORGANISM(S): Homo sapiens 
2007-06-01 | E-MEXP-973 | biostudies-arrayexpress
UnknownProteasome activity restricts lentiviral gene transfer into hematopoietic stem cells and is down-regulated by cytokines that enhance transduction.
Not available
S-EPMC1464833 | biostudies-literature
UnknownTargeted shock-and-kill HIV-1 gene therapy approach combining CRISPR activation, suicide gene tBid and retargeted adenovirus delivery.
Not available
S-EPMC10940146 | biostudies-literature
GenomicsWhole-exome ultra-high throughput sequencing in brain samples of suicide victims who had suffered from major depressive disorder and control subjects who had died from other causes
We carried out whole-exome ultra-high throughput sequencing in brain samples of suicide victims who had suffered from major depressive disorder and control subjects who had died from other causes. This study aimed to reveal the selective accumulation of rare variants in the coding and the UTR sequen...
EGAS00001002818 | EGA
UnknownInclusion of the Inducible Caspase 9 Suicide Gene in CAR Construct Increases Safety of CAR.CD19 T Cell Therapy in B-Cell Malignancies.
Not available
S-EPMC8560965 | biostudies-literature
GenomicsWhole-exome ultra-high throughput sequencing in brain samples of suicide victims who had suffered from major depressive disorder and control subjects who had died from other causes.
We carried out whole-exome ultra-high throughput sequencing in brain samples of suicide victims who had suffered from major depressive disorder and control subjects who had died from other causes. This study aimed to reveal the selective accumulation of rare variants in the coding and the UTR sequen...
EGAS00001003081 | EGA
UnknownRare protein-coding variants implicate genes involved in risk of suicide death.
Not available
S-EPMC9292859 | biostudies-literature
UnknownRetroviral gene therapy in Germany with a view on previous experience and future perspectives.
Not available
S-EPMC8455336 | biostudies-literature
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