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ProteomicsRapid differentiation of hiPSCs into functional oligodendrocytes using an OLIG2 synthetic modified messenger RNARapid differentiation of hiPSCs into functional oligodendrocytes using an OLIG2 synthetic modified messenger RNA
We show that a synthetic modified messenger RNA (smRNA)-based reprogramming method that leads to the generation of transgene-free OLs has been developed. An smRNA encoding a modified form of OLIG2, a key TF in OL development, in which the serine 147 phosphorylation site is replaced with alanine, OLI...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD036975 | Pride
Olig2  synthetic modified messenger rna (smrna)  human pluripotent stem cells (hipscs)  oligodendrocytes  cell transplantation 
UnknownRapid differentiation of hiPSCs into functional oligodendrocytes using an OLIG2 synthetic modified messenger RNA.
Not available
S-EPMC9568531 | biostudies-literature
TranscriptomicsSomatic Primary piRNA Biogenesis Driven by Cis-Acting RNA Elements and Trans- Acting Yb
Primary piRNAs in Drosophila ovarian somatic cells arise from piRNA cluster transcripts and the 3′ UTRs of a subset of mRNAs, including Traffic jam (Tj) mRNA. However, it is unclear how these RNAs are determined as primary piRNA sources. Here, we identify a cis-acting 100-nt fragment in the Tj 3′ UT...
ORGANISM(S): Drosophila melanogaster 
2015-06-05 | E-GEOD-69625 | biostudies-arrayexpress
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