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ProteomicsArchitecture of TAF11/TAF13/TBP complex suggests novel regulatory state of human general transcription factor TFIID
General transcription factor TFIID is a key component of RNA polymerase II transcription initiation in eukaryotic nuclei. Human TFIID is a megadalton-sized multiprotein complex comprising TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). TBP binds to core promoter DNA, recognizing the...
ORGANISM(S): Homo sapiens (Human) 
2017-11-15 | PXD005676 | Pride
Tfiid  taf11  taf13  dna binding  tata-binding protein  histone fold 
UnknownTAF11 Assembles the RISC Loading Complex to Enhance RNAi Efficiency.
Not available
S-EPMC4560963 | biostudies-literature
UnknownArchitecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.
Not available
S-EPMC5690282 | biostudies-literature
TranscriptomicsChIP-chip from H9 hESCs for RNA Polymerase II, TBP, TAF3, TAF5, TAF7, and TAF11
The general transcription factor TFIID is composed of the TATA-box-binding protein (TBP) and approximately 14 TBP-associated factors (TAFs). Here we find, unexpectedly, that undifferentiated human embryonic stem cells (hESCs) contain only six TAFs (TAFs 2, 3, 5, 6, 7 and 11), whereas following diffe...
ORGANISM(S): Homo sapiens 
2012-11-19 | E-GEOD-39312 | biostudies-arrayexpress
GenomicsHomo sapiens
ChIP-chip from H9 hESCs for RNA Polymerase II, TBP, TAF3, TAF5, TAF7, and TAF11
PRJNA170540 | ENA
GenomicsThe TFIID subunit Taf13 is dispensable for RNA polymerase II transcription, but essential for early embryogenesis (ChIP-Seq)
RNA polymerase II transcription initiation requires assembly of a preinitiation complex (PIC). According to the stepwise model of PIC assembly, TFIID is the first GTF to be recruited. TFIID comprises TBP and 13 TBP-associated factors (TAFs). We focused on TAF13, the smallest subunit of TFIID. Taf13 ...
ORGANISM(S): Mus musculus 
2025-06-18 | GSE254023 | GEO
GenomicsThe TFIID subunit Taf13 is dispensable for RNA polymerase II transcription, but essential for early embryogenesis [CUT&TAG]
RNA polymerase II (Pol II) transcription initiation requires assembly of a preinitiation complex (PIC) comprising the general transcription factors amongst which the multiprotein complex TFIID. TFIID comprises the TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). Recent cryo-electron ...
ORGANISM(S): Mus musculus 
2025-06-18 | GSE282035 | GEO
UnknownGenetic Association Analysis of Skin Traits and the TAF11 Gene in Shenxian Pigs
Not available
S-EPMC12937210 | biostudies-literature
TranscriptomicsThe TFIID subunit Taf13 is dispensable for RNA polymerase II transcription, but essential for early embryogenesis (RNA-Seq)
RNA polymerase II transcription initiation requires assembly of a preinitiation complex (PIC). According to the stepwise model of PIC assembly, TFIID is the first GTF to be recruited. TFIID comprises TBP and 13 TBP-associated factors (TAFs). We focused on TAF13, the smallest subunit of TFIID. Taf13 ...
ORGANISM(S): Mus musculus 
2025-06-18 | GSE254024 | GEO
UnknownHypomorphic Pathogenic Variants in TAF13 Are Associated with Autosomal-Recessive Intellectual Disability and Microcephaly.
Not available
S-EPMC5339287 | biostudies-literature
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