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GenomicsGenome-wide nucleosome, TFIIIC and TFIIIB occupancies in Saccharomyces cerevisiae
Paired-end sequencing study of nucleosomes and immuno-precipitated Tfc1 and Brf1 complexes from MNase-digested nuclei. Nucleosomal DNA, input DNA and DNA from immunopurified TFIIIB and TFIIIC complexes (IP) were subjected to paired-end sequencing.
ORGANISM(S): Saccharomyces cerevisiae 
2013-07-17 | E-GEOD-44586 | biostudies-arrayexpress
ProteomicsTFIIIC dinamically binds Alu elements to control gene expression through chromatin looping
Folding of the mammalian genome is governed by architectural proteins, such asCTCF. TFIIIC, a RNA polymerase III transcription factor, has been identified as aninsulator but its role in genome topology is totally unknown. Here, we show that TFIIICestablishes long-range genomic interactions that affe...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD011250 | Pride
Human Breast cancer Alu Tfiiic 
GenomicsGenomic binding of Pol III transcription machinery and relationship with TFIIS distribution in mouse embryonic stem cells
RNA polymerase (RNA Pol) III synthesizes the tRNAs, the 5S ribosomal RNA and a small number of untranslated RNAs. In vitro, it also transcribes short interspersed nuclear elements (SINEs). We investigated the distribution of RNA Pol III and its associated transcription factors on the genome of mouse...
ORGANISM(S): Mus musculus 
2011-09-16 | E-MTAB-767 | biostudies-arrayexpress
ProteomicsCharacterization of Tau95 led to the identification of a four-subunit TFIIIC complex in trypanosomatid parasites
RNA polymerase III (RNAP III) synthetizes small essential non-coding RNA molecules such as tRNAs and 5S rRNA. In yeast and vertebrates, RNAP III needs general transcription factors TFIIIA, TFIIIB and TFIIIC to initiate transcription. TFIIIC, composed of six subunits, binds to internal promoter eleme...
ORGANISM(S): Trypanosoma brucei brucei Leishmania major strain Friedlin 
2024-01-16 | PXD045036 | Pride
Leishmania major  trypanosoma brucei  rnap iii transcription  tfiiic  tau95 Orbitrap lumos 
GenomicsTFIIIC regulates SMC complex binding and 3D DNA contacts between tRNA genes [ChIP-Seq]
TFIIIC regulates SMC complex binding and 3D DNA contacts between tRNA genes [ChIP-Seq]
PRJNA1492859 | ENA
UnknownStructural insights into human TFIIIC promoter recognition.
Not available
S-EPMC11811891 | biostudies-literature
TranscriptomicsRNA Pol III transcriptomes and relationships to Pol II promoters, enhancer-binding factors and chromatin domains
RNA polymerase III transcribes many noncoding RNAs (e.g. tRNAs) important for translational capacity and other functions. Here, we localized RNA polymerase III, alternative TFIIIB complexes (BRF1/2) and TFIIIC in HeLa cells, determining the Pol III transcriptome, defining gene classes, and reveali...
ORGANISM(S): Homo sapiens 
2010-04-14 | E-GEOD-20609 | biostudies-arrayexpress
UnknownGlobal 'bootprinting' reveals the elastic architecture of the yeast TFIIIB-TFIIIC transcription complex in vivo.
Not available
S-EPMC3783186 | biostudies-literature
UnknownTranscription-independent TFIIIC-bound sites cluster near heterochromatin boundaries within lamina-associated domains in C. elegans.
Not available
S-EPMC6950938 | biostudies-literature
GenomicsTFIIIC regulates SMC complex binding and 3D DNA contacts between tRNA genes [ChIP-Seq]
Transcription factor IIIC (TFIIIC) is a multi-subunit protein complex that recruits RNA polymerase III (Pol III) to the majority of its target genes. Evolutionarily conserved overlap between TFIIIC binding sites and the structural maintenance of chromosomes (SMC) complexes suggested a role for TFIII...
ORGANISM(S): Caenorhabditis elegans 
2026-09-18 | GSE338224 | GEO
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