Sort   by:  
 Page size 
GenomicsTIMELESS promotes glioma stemness and malignancy through JAK-STAT3 pathway
TIMELESS promotes glioma stemness and malignancy through JAK-STAT3 pathway
PRJNA1480687 | ENA
GenomicsCircadian protein TIMELESS regulates synaptic plasticity and memory by modulating cAMP signaling
Circadian protein TIMELESS regulates synaptic plasticity and memory by modulating cAMP signaling
PRJNA858471 | ENA
TranscriptomicsTranscription profiling of response to tamoxifen in human ERa-positive postmenopausal breast tumor patients
Identification of HRPAP20 and TIMELESS as outstanding candidate markers to predict the response to tamoxifen in ERa-positive postmenopausal breast tumor patients
ORGANISM(S): Homo sapiens 
2007-10-09 | E-TABM-72 | biostudies-arrayexpress
GenomicsRNA-seq profiling of U-2 OS osteosarcoma cells expressing scrambled control or Timeless shRNA
RNA-seq profiling of U-2 OS osteosarcoma cells expressing scrambled control or Timeless shRNA
PRJNA1498013 | ENA
TranscriptomicsTIMELESS promotes glioma stemness and malignancy through JAK-STAT3 pathway
RNA-sequencing (RNA-seq) analysis was performed to identify TIMELESS-regulated gene signatures in mouse glioblastoma (GBM) CT2A cells. Timeless was originally identified as a core component of the circadian clock machinery, but its role in GBM stemness and malignancy has not been defined. To investi...
ORGANISM(S): Mus musculus 
2026-09-01 | GSE336084 | GEO
GenomicsTimeless collaborates with DDX11 to ensure processive replication of G4-forming DNA [RNA-seq]
Timeless collaborates with DDX11 to ensure processive replication of G4-forming DNA [RNA-seq]
PRJNA578917 | ENA
ProteomicsPRL-1 selectively dephosphorylates TIMELESS
The timing of behavior under natural light-dark conditions is a function of circadian clocks and photic input pathways. Yet a mechanistic understanding of how these pathways collaborate in animals is lacking. Here we demonstrate in Drosophila that the Phosphatase of Regenerating Liver-1 (PRL-1) sets...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-11-11 | PXD020986 | Pride
Circadian drosophila 
TranscriptomicsRNA-seq profiling of U-2 OS osteosarcoma cells expressing scrambled control or Timeless shRNA
Timeless and its fission yeast ortholog Swi1 are evolutionarily conserved components of the replication fork protection complex that ensures faithful DNA replication and genome stability. To elucidate the transcriptome-wide impact of Timeless depletion, we treated U-2 OS cells with lentiviruses expr...
ORGANISM(S): Homo sapiens 
2026-08-19 | GSE339246 | GEO
GenomicsCircadian protein TIMELESS regulates synaptic plasticity and memory by modulating cAMP signaling
Regulation of neurons by circadian clock genes is thought to contribute to the maintenance of neuronal functions that ultimately underlie animal behavior. However, the impact of circadian genes on cellular and molecular mechanisms that influnce synaptic plasticity and cognitive function remain to be...
ORGANISM(S): Mus musculus 
2023-04-17 | GSE208149 | GEO
TranscriptomicsTimeless collaborates with DDX11 to ensure processive replication of G4-forming DNA [RNA-seq]
Regions of DNA with the potential to form secondary structure pose a frequent and significant impediment to DNA replication that must be actively countered by cells in order to preserve genetic and epigenetic integrity. The fork protection complex (FPC), a conserved group of replisome-associated pro...
ORGANISM(S): Gallus gallus 
2020-07-01 | GSE139256 | GEO
Sort   by:  
 Page size