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MetabolomicsIntegration of metabolomics and transcriptome reveals toxicity variations of Alternaria
Alternaria, a widespread fungal genus, infects a wide range of crops and produces various toxins, such as Tentoxin (TEN), Tenuazonic acid (TeA), Alternariol (AOH) during infection, leading to a major concern about safety of these crops. Although the toxin-producing ability varies among different Alt...
2024-09-26 | MTBLS6073 | MetaboLights
MetabolomicsThe plasticity of the grapevine berry transcriptome
Vitis vinifera cultivar Corvina clone 48 berries were harvested from different vineyards, each located in one of the three most important wine production macro-areas of the Verona region: Bardolino, Valpolicella and Soave, on the basis of the site geographical coordinates. For each of the selected v...
2013-11-04 | MTBLS39 | MetaboLights
MetabolomicsMulti-omics uncovers formononetin's protection against antibiotic-induced liver injury via microbiota-metabolite-transcriptome coordination

Tetracycline antibiotics (TETs) cause hepatotoxicity via gut-liver axis disruption and oxidative stress. This study evaluated whether formononetin (FMN), a natural isoflavone, alleviates TET-induced liver injury through microbiota-metabolite-transcriptome coordination. Using network toxicology an...

2025-10-17 | MTBLS13161 | MetaboLights
MetabolomicsMulti-omics uncovers formononetin's protection against antibiotic-induced liver injury via microbiota-metabolite-transcriptome coordination

Tetracycline antibiotics (TETs) cause hepatotoxicity via gut-liver axis disruption and oxidative stress. This study evaluated whether formononetin (FMN), a natural isoflavone, alleviates TET-induced liver injury through microbiota-metabolite-transcriptome coordination. Using network toxicology an...

2025-10-14 | MTBLS13138 | MetaboLights
MetabolomicsCombined analysis of transcriptome and metabolome of large size triploid rainbow trout in different seasons
Seasonal temperature variation poses a major physiological challenge for cold-water aquaculture species, yet the molecular mechanisms underlying seasonal adaptation in large-sized triploid rainbow trout (Oncorhynchus mykiss) remain largely unexplored. Here, we integrated liver transcriptomics and LC...
2026-07-11 | MTBLS15014 | MetaboLights
MetabolomicsIntegrated analysis of transcriptome and metabolome reveals molecular responses to ammonia stress in the gills of Litopenaeus vannamei under low-salinity conditions

High ammonia nitrogen stress significantly compromises the survival of Litopenaeus vannamei under low-salinity conditions, posing a common challenge in low-salinity aquaculture. However, existing studies predominantly focus on ammonia nitrogen responses unde...

2026-04-10 | MTBLS14054 | MetaboLights
MetabolomicsComprehensive analysis of transcriptome and metabolome in Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma
Not available
ORGANISM(S): Homo sapiens 
ST000230 | MetabolomicsWorkbench
MetabolomicsMechanism of terpene formation in Pogostemon cablin cv. Jing Huoxiang revealed by metabolome and transcriptome analysis

Pogostemon cablin (Blanco) Benth. cv. 'Jing Huoxiang', is a valuable medicinal plant widely studied for its aboveground tissues, which are rich in bioactive compounds such as patchouli alcohol. However, systematic investigations into the biosynthesis of sesquiterpenes in its underground parts (ro...

2025-10-12 | MTBLS13122 | MetaboLights
MetabolomicsIntegrated metabolomics and transcriptome revealed the effect of fermented Lycium barbarum residue promoting Ovis aries immunity
Lycium barbarum residue contains abundant bioactive nutrients which can be used as feed supplement. This study investigated the effects of fermented and non-fermented Lycium barbarum residues (RFW and RW) on the meat quality and immunity of sheep (Ovis aries). Fifty-four Tan sheep were randomly divi...
2022-04-06 | MTBLS4507 | MetaboLights
MetabolomicsComparative Transcriptome and Energy Metabolome Profiling Unravel the Key Role of GlcN6P Metabolic Pathway in Resistance against Bacteriophage in Enterotoxigenic Escherichia coli

The rapid emergence of phage-resistant bacterial mutants is a major challenge for phage application in the food industry. The resistance mechanisms of Enterotoxigenic E. coli (ETEC) against phage infection are largely unknown. In Escherichia coli, RapZ regulates gluc...

2025-12-15 | MTBLS13411 | MetaboLights
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