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ProteomicsHuman UFSP1 is an active UFM1-specific protease
In order to confirm the translation initiation site of human UFSP1 (UFM1-specific protease 1), we sought to obtain direct evidence using mass spectrometry (MS) for peptide sequencing.
ORGANISM(S): Homo sapiens (Human) 
2022-04-08 | PXD033083 | Pride
Ufmylation  ufm1-specific protease  ufsp1  ufsp2 
UnknownLoss of Ufsp1 does not cause major changes at the neuromuscular junction.
Not available
S-EPMC12316231 | biostudies-literature
ProteomicsHuman UFSP1 is an active protease that regulates UFM1 maturation and UFMylation
An essential first step in the posttranslational modification of proteins with UFM1, UFMylation, is the proteolytic cleavage of pro-UFM1 to expose a C-terminal glycine. Of the two UFM1-specific proteases (UFSPs) identified in humans, only UFSP2 is reported to be active since the annotated sequence o...
ORGANISM(S): Homo sapiens (Human) 
2022-08-22 | PXD035142 | Pride
Ribosome Ufm1 Endoplasmic reticulum (er) Cysteine protease Ubiquitin like modifier 
UnknownHuman UFSP1 is an active protease that regulates UFM1 maturation and UFMylation.
Not available
S-EPMC9638016 | biostudies-literature
UnknownHuman UFSP1 translated from an upstream near-cognate initiation codon functions as an active UFM1-specific protease.
Not available
S-EPMC9168615 | biostudies-literature
ProteomicsIdentification of interacting proteins for UFM1-specific protease 1 (UfSP1) using proximity labeling technique
In this project, we used label-free quantitative proteomics to identify UfSP1-interacting proteins in HEK293T cells.
ORGANISM(S): Homo Sapiens 
2023-01-31 | PXD039750 |
UnknownSystematic Analysis of UFMylation Family Genes in Tissues of Mice with Metabolic Dysfunction-Associated Steatotic Liver Disease.
Not available
S-EPMC11765366 | biostudies-literature
UnknownMallory-Denk Body (MDB) formation modulates Ufmylation expression epigenetically in alcoholic hepatitis (AH) and non-alcoholic steatohepatitis (NASH).
Not available
S-EPMC4262563 | biostudies-literature
UnknownStructure of ubiquitin-fold modifier 1-specific protease UfSP2.
Not available
S-EPMC3060479 | biostudies-literature
UnknownMapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity.
Not available
S-EPMC4947558 | biostudies-literature
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