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ProteomicsStudy of molecular mechanisms in lung injury due to ultra-high and conventional dose rate pulsed radiation based on 4D-DIA proteomics
Objective: To investigate the mechanism of ultra-high dose rate pulsed radiation in radiation-induced lung injury (RILI), providing an experimental and theoretical basis for the application of FLASH-RT in radiotherapy. Methods: C57BL/6J mice were randomly divided into three groups: a sham group, a F...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD057784 | Pride
Radiation-induced lung injury  ultra-high dose rate  flash radiotherapy  fibrosis  flash effect 
GenomicsHuman enteroids as a tool to study conventional and ultra-high dose rate radiation
Human enteroids as a tool to study conventional and ultra-high dose rate radiation
PRJNA1150164 | ENA
TranscriptomicsHuman enteroids as a tool to study conventional and ultra-high dose rate radiation
Radiation therapy, one of the most effective therapies to treat cancer, is highly toxic to healthy tissue. The delivery of radiation at ultra-high dose rates, FLASH radiation therapy (FLASH), has been shown to maintain therapeutic anti-tumor efficacy while sparing normal tissues compared to conventi...
ORGANISM(S): Homo sapiens 
2024-09-16 | GSE275276 | GEO
TranscriptomicsTranscriptome profiling of wheat seedlings following treatment with ultra-high diluted Arsenicum trioxide
A recently developed plant model [Betti et al., 2010 TheScientificWorldJOURNAL, 10, 2330M-^V2347] was used for identifying differentially expressed genes associated with plant response to ultra-high diluted (beyond the Avogadro limit) treatments. Seeds of common wheat (Triticum aestivum L.), previou...
ORGANISM(S): Triticum aestivum 
2015-03-12 | E-MEXP-3666 | biostudies-arrayexpress
MetabolomicsMetabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine UPLC-MS assay)
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non relevant doses or in combination with other r...
2019-05-28 | MTBLS596 | MetaboLights
UnknownUltra-high dose rate FLASH irradiator at the radiological research accelerator facility.
Not available
S-EPMC9780319 | biostudies-literature
UnknownKey changes in the future clinical application of ultra-high dose rate radiotherapy.
Not available
S-EPMC10628486 | biostudies-literature
UnknownFirst in vitro and in vivo experiments with ultra high-dose rate oxygen ion radiotherapy.
Not available
S-EPMC12280408 | biostudies-literature
UnknownOxygen consumption measurements at ultra-high dose rate over a wide LET range.
Not available
S-EPMC11788059 | biostudies-literature
UnknownHuman enteroids as a tool to study conventional and ultra-high dose rate radiation.
Not available
S-EPMC10594601 | biostudies-literature
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