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TranscriptomicsExpression data from Versican (VCAN) protein treated ovarian cancer cell line OVCA433
Advanced ovarian cancer is the most lethal gynecologic malignancy in the United States. Currently patients are treated by surgical cytoreductive surgery with the aim of reducing tumor burden to microscopic disease followed by adjuvant combined treatment with a platinum and taxane containing chemothe...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-40241 | biostudies-arrayexpress
GenomicsSingle-cell RNA sequencing of Versican (Vcan) knockout mice after cardiac ischemia.
Single-cell RNA sequencing of Versican (Vcan) knockout mice after cardiac ischemia.
PRJEB61792 | ENA
ProteomicsVersican in murine cell line supernatants
The tumor derived Versican (VCAN) can be a possible mediator of the host NF-κB pathway in cancer pathogenesis. In this context, we defined VCAN function in the pathogenesis development in vitro with cell lines as well as in vivo with mouse model. We used the proteomic technique to quantify VCAN inte...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD019883 | Pride
Vcan  versican  mouse  cancer  cell line 
ProteomicsAcellular ECM Proteomics: Versican expression from lung fibroblasts is an autologous fibrotic brake
The activation and accumulation of lung fibroblasts, leading to excessive extracellular matrix (ECM) deposition, is a pathogenic hallmark of Idiopathic Pulmonary Fibrosis (IPF), a lethal and currently incurable disease. The collagen-rich fibrotic ECM perpetuates fibroblast activation and accumulatio...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD063546 | Pride
Aecm Pulmonary fibrosis  extracellular matrix (ecm)  lung fibroblasts  podosomes  ecm invasion  versican (vcan)  hyaluronan (ha)  collagens 
ProteomicsVersican regulates Collagen fibrillation and Tenascin-C expression, suppressing podosome formation and pulmonary fibrosis
The activation and accumulation of lung fibroblasts, leading to aberrant deposition of extracellular matrix (ECM) components, is a pathogenic hallmark of Idiopathic Pulmonary Fibrosis (IPF), a lethal and currently incurable disease. ECM deposition perpetuates fibroblast activation and stimulates ECM...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD060583 | Pride
Pulmonary fibrosis  extracellular matrix (ecm)  lung fibroblasts  podosomes  ecm invasion  versican (vcan)  hyaluronan (ha)  collagen (col)  tenascin-c (tnc) 
GenomicsMolecular Characterization of auditory nerve with Versican deficiency
Molecular Characterization of auditory nerve with Versican deficiency
PRJNA503256 | ENA
UnknownAssociation of Versican (VCAN) gene polymorphisms rs251124 and rs2287926 (G428D), with intracranial aneurysm.
Not available
S-EPMC4287847 | biostudies-literature
TranscriptomicsTranscriptional profiling of turkey muscle satellite cells transfected with versican-siRNA during proliferation and differentiation
In this study, we directly compared turkey muscle satellite cell gene expression between satellite cells with the gene versican (VCAN) knocked down by siRNA transfection and those transfected with a lipofectamine control using our 6K Turkey Skeletal Muscle Long Oligo (TSKMLO) microarray (GPL9788). ...
ORGANISM(S): Meleagris gallopavo 
2012-05-31 | E-GEOD-36365 | biostudies-arrayexpress
UnknownVersican facilitates chondrocyte differentiation and regulates joint morphogenesis.
Not available
S-EPMC2898371 | biostudies-literature
TranscriptomicsExpression data from Versican (VCAN) protein treated ovarian cancer cell line OVCA433
Advanced ovarian cancer is the most lethal gynecologic malignancy in the United States. Currently patients are treated by surgical cytoreductive surgery with the aim of reducing tumor burden to microscopic disease followed by adjuvant combined treatment with a platinum and taxane containing chemothe...
ORGANISM(S): Homo sapiens 
2013-12-31 | GSE40241 | GEO
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