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Loss of voltage dependent anion channel 1 affects mitochondrial bioenergetics in rat dopamine cells
Voltage-Dependent Anion Channel isoforms (VDAC1, VDAC2, VDAC3) are relevant component of the outer mitochondrial membrane and play crucial role in cellular processes, in regulation of metabolism and in survival pathways. Recently, we reported the characterization of the oxidation pattern of cysteine...
ORGANISM(S): Rattus rattus (Black rat) 
2024-06-16 | PXD044041 | Pride
Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis
Voltage-Dependent Anion Channels, the most abundant proteins of the mitochondrial outer membrane, are responsible for exchange of ions and metabolites between cytosol and mitochondria. They participate in the control of glycolytic metabolism through interaction with numerous enzymes and play a key r...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-09-08 | PXD064110 | Pride
Voltage dependent anion channel 1 (VDAC1) is a multi-functional protein that regulates mitochondrial membrane potential, calcium regulation, and apoptosis. VDAC1 also interacts with a number of signaling pathways important for energy homeostasis and proteins involved in neurodegenerative diseases su...
ORGANISM(S): Rattus norvegicus 
2019-07-31 | GSE118737 | GEO
Changes in gravitational force such as that experienced by astronauts during space flight induce a redistribution of fluids from the caudad to the cephalad portion of the body together with an elimination of normal head-to-foot hydrostatic pressure gradients. To assess brain gene profile changes ass...
ORGANISM(S): Mus musculus 
In plant cells, the ALMTs are key plasma and vacuolar membranes anion channels regulating plant responses to the environment. Vacuolar ALMTs control stomata aperture and anion accumulation in guard cells. The activation of vacuolar ALMTs is voltage and malate dependent, but the underlying mechanisms...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-03-04 | PXD059651 | Pride
The voltage-dependent anion-selective channels (VDACs), also known as eukaryotic porins, are pore-forming proteins which allow the passage of ions and small molecules across the outer mitochondrial membrane (OMM). They are involved in complex interactions regulating organelle and cellular metabolism...
ORGANISM(S): Homo sapiens (Human) 
2020-03-09 | PXD017482 | Pride
We have found that the cell yield of oligodendrocyte precursor cells (OPCs) are higher in 31.5 degC than in 37 degC not by suppression of apoptosis but by enhancement of proliferation. Here, we performed transcriptome analysis using Affymetrix GeneChip on the primary cultured oligodendrocyte precurs...
ORGANISM(S): Mus musculus 
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