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MetabolomicsIntestinal lipid oxidation after VSG
Not available
ORGANISM(S): Rattus norvegicus 
ST000297 | MetabolomicsWorkbench
GenomicsTrypanosoma brucei VSG Switching
Trypanosoma brucei VSG Switching - CRISPR/Cas9
PRJEB40415 | ENA
TranscriptomicsRNAi knock-down of VSG in T. brucei for 1 or 3 days
As an additional strategy for investigating T. brucei transcriptome responsiveness, the mRNA of a highly important protein, the variant surface glycoprotein (VSG) the major surface protein in the bloodstream stage, was suppressed with RNAi. VSG RNAi results in arrest of cell cycle progression...
ORGANISM(S): Trypanosoma brucei 
2008-06-26 | E-MEXP-1528 | biostudies-arrayexpress
GenomicsVSG seq T. brucei
Sequencing of the expressed VSGs in T. brucei cells where monoallelic VSG expression has been disrupted.
PRJEB43907 | ENA
ProteomicsA non-coding role for trypanosome VSG transcripts in allelic exclusion
Bloodstream-form African trypanosomes display mono-telomeric expression of a Variant Surface Glycoprotein (VSG) gene in an inter-chromosomally bridged transcription and splicing compartment, such that the dominant gene produces 10,000 times more transcript than excluded VSG genes. Antigenic variatio...
ORGANISM(S): Trypanosoma brucei 
2025-03-11 | PXD060524 | Pride
Antigenic variation Trypanosoma brucei. Cncrna Monoallelic 
UnknownVSG mRNA levels are regulated by the production of functional VSG protein.
Not available
S-EPMC7871013 | biostudies-literature
ProteomicsUp regulated Variant Surface Glycoproteins under TDP1 overexpression
Trypanosoma brucei parasites successfully evade the host immune system by periodically switching the dense coat of Variant Surface Glycoproteins (VSG) at the cell surface. Each parasite expresses VSGs in a monoallelic fashion that is tightly regulated. The consequences of exposing multiple VSGs duri...
ORGANISM(S): Trypanosoma brucei 
2019-09-13 | PXD014803 | Pride
Trypanosoma brucei Vsg Tdp1 
GenomicsGene expression profile chqnge of intestinal stem cells after VSG bariatric surgery
Gene expression profile chqnge of intestinal stem cells after VSG bariatric surgery
PRJNA725702 | ENA
GenomicsTranscription dependent loss of an ectopic VSG
Loss of an ectopic VSG is dependent on active transcription and does not disrupt the number or variety of templates used to repair a BES DSB
PRJEB49263 | ENA
TranscriptomicsGene expression profiling of the ileum following vertical sleeve gastrectomy compared to pair-fed sham surgery controls in mice with high-fat diet-induced obesity.
We report the expression profiles of ileal samples extracted from obese male C57Bl6 mice following vertical sleeve gastrectomy or sham surgery, focusing of gene signatures indicative of altered bile acid metabolism. We induced obesity in male C57bl6 mice through a high-fat diet. At 8 weeks, they we...
ORGANISM(S): Mus musculus 
2014-03-27 | E-GEOD-53782 | biostudies-arrayexpress
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