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TranscriptomicsFibronectin regulates Wnt7a signaling and satellite cell expansion
The influence of the extracellular matrix (ECM) within the stem cell niche remains poorly understood. We found that Syndecan-4 (Sdc4) and Frizzled-7 (Fzd7) form a coreceptor complex in satellite cells and that binding of the ECM glycoprotein Fibronectin (FN) to Sdc4 stimulates the ability of Wnt7a t...
ORGANISM(S): Mus musculus 
2014-07-11 | E-GEOD-59272 | biostudies-arrayexpress
UnknownWnt7a Counteracts Cancer Cachexia.
Not available
S-EPMC7005483 | biostudies-literature
TranscriptomicsFibronectin regulates Wnt7a signaling and satellite cell expansion
The influence of the extracellular matrix (ECM) within the stem cell niche remains poorly understood. We found that Syndecan-4 (Sdc4) and Frizzled-7 (Fzd7) form a coreceptor complex in satellite cells and that binding of the ECM glycoprotein Fibronectin (FN) to Sdc4 stimulates the ability of Wnt7a t...
ORGANISM(S): Mus musculus 
2014-07-11 | GSE59272 | GEO
UnknownWNT7A/B promote choroidal neovascularization.
Not available
S-EPMC6110966 | biostudies-literature
TranscriptomicsRNA-seq analysis in Cornea epithelial cells (CECs), skin epithelial cells (SECs), LSCs after knocking down PAX6 (3-D shPAX6 LSCs) and SESCs transduced with PAX6(3-D PAX6+ SESCs) upon 3-D differentiation
Purpose: We find that Wnt7a-PAX6 axis determine corneal epithelial cell fate. To obtain global evidence for successful cell fate conversion, we performed gene expression profiling by RNA-seq on CECs, SECs, and LSCs after knocking down PAX6 and on SESCs transduced with PAX6 upon 3-D differentiation. ...
ORGANISM(S): Homo sapiens 
2014-07-11 | E-GEOD-54322 | biostudies-arrayexpress
GenomicsA Wnt7a-Hoxa13 pathway for Müllerian duct fusion at the body midline for uterine morphogenesis
A Wnt7a-Hoxa13 pathway for Müllerian duct fusion at the body midline for uterine morphogenesis
PRJNA1418746 | ENA
UnknownWnt7a is required for regeneration of dystrophic skeletal muscle.
Not available
S-EPMC11656582 | biostudies-literature
OtherA Wnt7a-Hoxa13 pathway for Müllerian duct fusion at the body midline for uterine morphogenesis
During embryonic development, the Müllerian ducts and adjacent mesenchyme differentiate into the tissues of the oviducts, uterus, cervix, and upper vagina. Variations in the fusion process can alter typical uterine morphology, correlating with an increased incidence of infertility, high-risk pregnan...
ORGANISM(S): Mus musculus 
2026-02-07 | GSE318449 | GEO
UnknownHIF-1α Directly Controls WNT7A Expression During Myogenesis.
Not available
S-EPMC7686515 | biostudies-literature
UnknownAlterations of the WNT7A gene in clear cell renal cell carcinomas.
Not available
S-EPMC3466251 | biostudies-literature
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