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MetabolomicsMultiomic Approach to Analyze Infant Gut Microbiota: Experimental and Analytical Method Optimization

BACKGROUND: The human intestinal microbiome plays a central role in overall health status, especially in early life stages. 16S rRNA amplicon sequencing is used to profile its taxonomic composition; however, multiomic approaches have been proposed as the most accurate methods for...

2021-08-18 | MTBLS2942 | MetaboLights
ProteomicsOptimization of statistical methods impact on quantitative proteomics data
As tools for quantitative label-free mass spectrometry (MS) rapidly develop a consensus about the best practices is not apparent. In the work described here we compared five popular statistical methods for detecting differential protein expression from quantitative MS data using both controlled expe...
ORGANISM(S): Candida albicans (Yeast) 
2020-01-13 | PXD002099 | Pride
Reproducibility Statistical methods Proteomics Quantitative analysis Rots Label-free mass spectrometry 
ProteomicsOptimization of a Top-Down Proteomics Platform for Closely-Related Pathogenic Bacteria Discrimination
The current technique used for microbial identification in hospitals is MALDI-TOF MS. However, it suffers from important limitations, in particular for closely-related species or when the database used for the identification lacks the appropriate reference. In this work, we set up a high throughput ...
ORGANISM(S): Shigella flexneri Salmonella enterica subsp. enterica serovar Muenchen Salmonella enterica subsp. enterica serovar Enteritidis Salmonella enterica subsp. enterica serovar Typhimurium Escherichia coli O26:H11 Shigella sonnei Escherichia coli O157:H7 Salmonella enterica subsp. enterica serovar Newport Escherichia coli 
2020-09-24 | PXD019247 | Pride
Mass spectrometry Optimization Top-down proteomics Bacteria 
UnknownAn Intra-Cycle Optimal Control Framework for Ventricular Assist Devices Based on Atrioventricular Plane Displacement Modeling.
Not available
S-EPMC8671277 | biostudies-literature
ProteomicsOptimization of Elution Conditions for Biotinylated Peptides from Tamavidin 2-REV
We attempted to optimize the conditions for competitive elution of biotinylated peptides from the Tamavidin 2-REV beads. First, to optimize the temperature at which biotinylated peptides were eluted from the beads, biotinylated peptides were eluted with the biotin solution at 4, 37, 56, and 95 ºC. S...
ORGANISM(S): Mus Musculus (mouse) 
2022-08-25 | PXD035219 | JPOST Repository
UnknownAccelerated Chemical Reaction Optimization Using Multi-Task Learning.
Not available
S-EPMC10214532 | biostudies-literature
UnknownScheduling optimization of ship plane block flow line considering dual resource constraints.
Not available
S-EPMC11680824 | biostudies-literature
UnknownMultiobjective design optimization of parabolic trough collectors.
Not available
S-EPMC9675770 | biostudies-literature
UnknownLeveraging an intelligent slug flow platform for self-optimization of reaction systems with categorical variables.
Not available
S-EPMC12550597 | biostudies-literature
UnknownOptimization strategies of in-tube extraction (ITEX) methods.
Not available
S-EPMC4545181 | biostudies-literature
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