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ProteomicsZO-1 phosphorylation upon ERK activation
This dataset was generated to identify phosphorylation sites of ZO-1 regulated by ERK signaling. Cells were treated with TPA alone or with TPA in combination with the MEK inhibitor PD0325901, followed by phosphopeptide enrichment and LC–MS/MS analysis. TPA activates multiple kinases including ERK, w...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2026-04-17 | PXD076445 | Pride
Erk Zo-1 Phosphorylation 
ProteomicsProfiling ZO-1 interactome in endothelial cells
ZO-1 immunoprecipitation samples from BAECs, treated or not with VEGF, were analyzed using LC-MS/MS.
ORGANISM(S): Bos taurus (Bovine) 
2024-05-22 | PXD029332 | Pride
Zo-1 Proteomics Endothelial cells 
ProteomicsNADPH Oxidase 1 (NOX1)-PKCdelta dependent ZO-1 phosphorylation mediates IL-33-induced inner blood-retinal barrier disruption in proliferative retinopathies.
Proliferative retinopathies are associated with abnormal angiogenesis that can result in visual impairment or vision loss. The tight junction complex regulates blood-retinal barrier integrity; however, its role in proliferative retinopathies is still at an early stage. Here, we employed human retina...
ORGANISM(S): Homo sapiens (Human) 
2025-10-14 | PXD060282 | Pride
Tight junction  zo-1  pkc delta  proliferative retinopathy  vascular leakage 
GenomicsSHED-derived exosomes ameliorate hyposalivation caused by Sjögren syndrome via Akt/GSK-3β/Slug-mediated ZO-1 expression.
SHED-derived exosomes ameliorate hyposalivation caused by Sjögren syndrome via Akt/GSK-3β/Slug-mediated ZO-1 expression.
PRJNA820435 | ENA
UnknownVCAM-1 induces signals that stimulate ZO-1 serine phosphorylation and reduces ZO-1 localization at lung endothelial cell junctions.
Not available
S-EPMC6016384 | biostudies-literature
UnknownDifferent effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion.
Not available
S-EPMC4612710 | biostudies-literature
GenomicsHeart Failure Pleural Fluid Impairs Endothelial Barrier through miR 501-3p Mediated ZO 1 Remodeling
Heart Failure Pleural Fluid Impairs Endothelial Barrier through miR 501-3p Mediated ZO 1 Remodeling
PRJNA1425950 | ENA
GenomicsSHED-derived exosomes ameliorate hyposalivation caused by Sjögren syndrome via Akt/GSK-3β/Slug-mediated ZO-1 expression.
SHED-exos can ameliorate Sjögren syndrome-induced hyposalivation through miRNAs mediated Akt/Slug/ZO-1 expression.
ORGANISM(S): Homo sapiens 
2022-04-01 | GSE199497 | GEO
UnknownNeuronal connexin36 association with zonula occludens-1 protein (ZO-1) in mouse brain and interaction with the first PDZ domain of ZO-1.
Not available
S-EPMC1805788 | biostudies-literature
UnknownMolecular alterations associated with pathophysiology in liver-specific ZO-1 and ZO-2 knockout mice.
Not available
S-EPMC11930773 | biostudies-literature
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