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Multi-dimensional transcriptome analysis of an intact hematopoietic organ for HSPC expansion [10x]
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation[10x]
We investigate the single-cell landscape of the inflammatory mouse tumor model MC38, a C57BL/6 tumor cell line derived from colon adenocarcinoma. MC38 (diluted in HBSS and matrigel) was inoculated in the right unilateral flank (in the border of positions B2 and B3) of C57BL/6 mice (ref Study 16-3384...
ORGANISM(S): Mus musculus 
Using an in vivo mouse model of stretch-mediated skin expansion, we have performed scRNAseq (10x Genomics) on control (CTRL) skin and expanded (EXP) skin at 3 time points: day 1, day 2 and day 4. Stretch-mediated expansion is used in reconstructive and cosmetic surgeries to produce extra skin, howev...
ORGANISM(S): Mus musculus 
2026-05-14 | GSE285079 | GEO
To investigate the peculiarity of CHT HSPCs, as well as the interaction of CHT niche and HSPCs at higher resolution, we performed scRNA-seq with zebrafish CHT.
ORGANISM(S): Danio rerio 
2019-04-23 | GSE120503 | GEO
We used a 10X Genomics single-cell RNA sequencing approach to study transcriptional profiling of coronary developmental stages in zebrafish comparing data from initiation (10 mm), establishment (14 mm), expansion (18 mm) and maturation (28 mm).
ORGANISM(S): Danio rerio 
2025-12-17 | GSE298874 | GEO
Intermuscular adipose tissue (IMAT) accumulation within skeletal muscle is associated with cardiometabolic disease, yet its spatial organization and molecular drivers remain poorly characterized. To map IMAT expansion within the quadriceps muscle architecture, spatial transcriptomics was performed o...
ORGANISM(S): Mus musculus 
Intestinal regeneration after injury can occur through the expansion of surviving intestinal stem cells (ISCs) or via dedifferentiation of progenitor cells. To assess whether Lgr5⁺ ISCs that persist after irradiation—and their progeny—undergo long-term transcriptomic and epigenetic alterations, we p...
ORGANISM(S): Mus musculus 
2026-09-16 | GSE302685 | GEO
This study shows the pronounced expansion of CD8 T cell clones at sites of active inflammation within the joints of psoriatic arthritis (PsA) patients compared to blood, and characterises the gene expression of expanded clones using droplet based single cell RNA sequencing. Mononuclear cells were se...
ORGANISM(S): Homo sapiens 
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