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ProteomicsRapid and accurate detection of aminoglycoside modifying enzymes and 16S ribosomal RNA methyltransferases by targeted LC-MS/MS
New and rapid diagnostic methods are needed for the detection of antimicrobial resistance to aid in the curbing of drug-resistant infections. Targeted LC-MS/MS is a method that could serve this purpose, as it can detect specific peptides of resistance mechanisms with high accuracy. In the current st...
ORGANISM(S): Escherichia coli Klebsiella pneumoniae BIDMC 40 
2021-04-30 | PXD024339 | Pride
E. coli Aminoglycosides Parallel reaction monitoring Aminoglycoside modifying enzymes Liquid chromatography mass spectrometry K. pneumoniae 16s ribosomal rna methyltransferases Antimicrobial resistance 
UnknownRibosomal RNA guanine-(N2)-methyltransferases and their targets.
Not available
S-EPMC1874633 | biostudies-literature
UnknownDesign, Synthesis, and Evaluation of Novel Inhibitors of Aminoglycoside-Resistance 16S Ribosomal RNA Methyltransferases.
Not available
S-EPMC12698113 | biostudies-literature
Unknown30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC.
Not available
S-EPMC10288597 | biostudies-literature
Unknown30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC.
Not available
S-EPMC10054953 | biostudies-literature
UnknownOne Health Spread of 16S Ribosomal RNA Methyltransferase-Harboring Gram-Negative Bacterial Genomes: An Overview of the Americas.
Not available
S-EPMC10536106 | biostudies-literature
UnknownMechanism of 30S subunit recognition and modification by the conserved bacterial ribosomal RNA methyltransferase RsmI.
Not available
S-EPMC12407886 | biostudies-literature
MetabolomicsMechanisms of hepatic steatosis in chickens: integrated analysis of the host genome, molecular phenomes and gut microbiome

Hepatic steatosis is the initial manifestation of abnormal liver functions and often leads to liver diseases such as non-alcoholic fatty liver disease in humans and fatty liver syndrome in animals. In this study, we conducted a comprehensive analysis of a large chicken population consisting of 70...

2023-07-24 | MTBLS7808 | MetaboLights
UnknownA paradigm for local conformational control of function in the ribosome: binding of ribosomal protein S19 to Escherichia coli 16S rRNA in the presence of S7 is required for methylation of m2G966 and blocks methylation of m5C967 by their respective methyltransferases.
Not available
S-EPMC332521 | biostudies-literature
UnknownIdentification and characterization of RsmE, the founding member of a new RNA base methyltransferase family.
Not available
S-EPMC1383581 | biostudies-literature
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