Aminoglycosides

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Metabolite Name

Valine (2)
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5-benzhydryl-1-(phenylsulfonyl)-1H-pyrazole (1)
3-(5-pyridin-3-yl-2-thienyl)prop-2-yn-1-ol (1)
2-[amino(3-chloroanilino)methylene]malononitrile (1)
10b-methyl-1,5,6,10b-tetrahydroimidazo[2,1-a]isoquinolin-2(3H)-one (1)
N1-(5-methylisoxazol-3-yl)-2-tetrahydro-1H-pyrrol-1-ylacetamide (1)
2-Styryl-1,3-benzoxazole (1)
4'-propyl[1,1'-biphenyl]-4-carboxamide (1)
1-Nitrosopyrrolidine (NPYR) (1)
¦Á-Hydroxyhippuric acid (1)
1-methyl-2-oxo-1,2-dihydroquinolin-4-yl N,N-dimethylcarbamate (1)
2-(4-methylphenyl)-2-oxoethyl thiocyanate (1)
4-methyl-6-[(4-methylphenyl)thio]-2-(2-pyridyl)pyrimidine (1)
3-(2,6-difluorophenyl)-4-ethyl-1H-pyrazole (1)
8-amino-5-hydroxy-4-iminonaphthalen-1-one (1)
4-fluoro-1,2-dihydro-3H-indazol-3-one (1)
4-methylpyridine-3-sulfonic acid (1)
7-chloro-4-[(5-propyl-2-pyrimidinyl)oxy]quinazoline (1)
3-(dimethylamino)-2-[3-(trifluoromethyl)phenyl]acrylonitrile (1)
2-(4-methylphenyl)imidazo[1,2-a]pyrimidine (1)
6,9-dimethoxy-11H-indeno[1,2-b]quinoxalin-11-one (1)
2-{[(2-hydroxy-1-naphthyl)methylidene]amino}isoindoline-1,3-dione (1)
1-allyl-4,5-diphenyl-2-(2-thienyl)-1H-imidazole (1)
2-methyl-1H-benzimidazole-5-carboxylic acid (1)
N1-bicyclo[2.2.2]oct-2-ylbenzamide (1)
N1-(2-cyanoethyl)-3-amino-4-chlorobenzene-1-sulfonamide (1)
3'-Dephospho-CoA (1)
2-[2-(2-pyridyloxy)ethoxy]pyridine (1)
Dihexylamine (1)

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bacteria (49)

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Lab affiliation

Genomics Research Center, Academia Sinica, Taipei, 11529 Taiwan (3)
Lab. Neuro-oncologie en klinische en kanker proteomics Department of Neurology Erasmus MC (2)
1Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium (1)
Associate Professor, Department of Biology, IISER Pune (1)
Biochemistry and Neurobiology Group, Department of Analytical Chemistry and Biochemistry, Faculty of Material Sciences and Ceramics, AGH University of Krakow, Mickiewicza 30 avenue, 30-059 Krakow, Poland (1)
Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, US (1)
Department of Physical Biochemistry, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Goettingen, Germany (1)
Department of Physical Biochemistry, Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11 37077 Goetttingen (1)
Department of Physical Biochemistry, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany (1)
Département Génomes et Génétique, Institut Pasteur, UMR3525, CNRS, Unité Plasticité du Génome Bactérien, 75015, Paris, France (1)
Erasmus MC Neurology Lab. Neuro-Oncology and Clinical and Cancer Proteomics (1)
Lanzhou University, Lanzhou, Gansu, China (1)
Max Planck Institute for Biophysical Chemistry Department of Physical Biochemistry Am Fassberg 11 37077 Goettingen Germany (1)
Research Unit in Biology of Microorganisms (URBM), Department of Biology, Namur Research Institute for Life Sciences (NARILIS), University of Namur, Namur, Belgium. (1)
The First Hospital of Changsha (1)
University of Zurich, Institute of Medical Microbiology (1)
William A. Brookshire Department of Chemical and Biomolecular Engineering, University of Houston, Houston, TX, US (1)

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Proteomic analysis of carbapenem-resistant Klebsiella pneumoniae exposure to tigecycline and aminoglycosides

ORGANISM(S): Klebsiella Pneumoniae Subsp. Pneumoniae Hs11286

2022-01-17 | PXD031030 |

Transcription profiling of human liver to evaluation of RNA binding specificity of aminoglycosides with DNA microarrays

We have developed methods for using DNA array technology to probe the entire transcriptome to determine RNA-binding specificity of ligands. Two methods were investigated. In the first, the RNA-binding aminoglycoside antibiotic tobramycin was covalently linked to magnetic beads. The beads were bou...

ORGANISM(S): Homo sapiens

2008-06-13 | E-GEOD-5111 | biostudies-arrayexpress

Selective silencing of antibiotic-tethered ribosomes as a resistance mechanism against aminoglycosides

Antibiotic resistance is a growing threat, underscoring the need to understand the underlying mechanisms. Aminoglycosides kill bacteria by disrupting translation fidelity, leading to the synthesis of aberrant proteins. Surprisingly, mutations in fusA, a gene encoding translation elongation factor G ...

ORGANISM(S): Escherichia coli

2025-09-05 | PXD067947 | Pride

Aminoglycosides: An Overview.

Not available

S-EPMC4888811 | biostudies-literature

Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 4]

PRJNA576652 | ENA

Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 2]

PRJNA576650 | ENA

Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 3]

PRJNA576651 | ENA

Aminoglycosides induce a bacterial senescent state that increases antibiotic tolerance in treatment-naïve cells

PRJNA764249 | ENA

Queuosine modification of tRNA-Tyr elicits translational reprogramming and enhances growth of Vibrio cholerae with aminoglycosides

Tgt is responsible for the queuosine (Q) modification of the guanine (G) in tRNAs with GUN anti-codon. We have previously identified tgt as being vital for growth in presence sub-lethal concentrations of aminoglycosides in Vibrio cholerae. Here we further explore the role of Q modification in transl...

ORGANISM(S): Vibrio cholerae O1

2024-12-11 | PXD035297 | Pride

Aminoglycosides Trna-tyr Queuosine modification

Antibacterial Efficacies of Nanostructured Aminoglycosides.

Not available

S-EPMC8851436 | biostudies-literature

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