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TranscriptomicsExpression profiling of ccRCC samples treated with anti-VEGF therapies reveals distinct markers
Metastatic renal cell carcinoma (mRCC) patients treated with anti-vascular endothelial growth factor (VEGF) therapies demonstrate promising outcomes but not all patients benefit. Factors that predict response remain to be elucidated. Nephrectomy material from 37 patients with mRCC receiving bevacizu...
ORGANISM(S): Homo sapiens 
2011-01-07 | E-GEOD-25698 | biostudies-arrayexpress
ProteomicsProteomics and immunoproteomics of Anoplocephala perfoliata
Anoplocephala perfoliata is a common tapeworm in horse with an ability to cause colic and increase mortality. At present, current diagnostic methods are not sensitive enough to detect A. perfoliata and immunoreactive excretory/secretory (E/S) proteins produced by this parasite, which comprise the mo...
ORGANISM(S): Anoplocephala perfoliata 
2022-11-11 | PXD029144 | Pride
Perseus E/s proteins Tapeworm Parasite Horse Maxquant Lc-ms/ms 1d immunoblotting 
TranscriptomicsGene expression profiling upon PI3K inhibition using different inhibitors
Activation of the phosphoinositide 3-kinase (PI3K)/Akt signaling pathway is one the most frequent genetic events in human cancer. Therefore, the development of PI3K inhibitors has attracted much attention. We previously described the pyrazolopyrimidine derivative ETP-45658 as a potent inhibitor of P...
ORGANISM(S): Homo sapiens 
2014-04-08 | E-GEOD-56579 | biostudies-arrayexpress
ProteomicsNaringenin targets PI3K p85alpha to suppress PI3K/AKT signaling pathway and ameliorate disordered MMP-9 secretion in cigarette smoke extract-induced alveolar macrophages in vitro
Naringenin has demonstrated potential therapeutic effects against cigarette smoke-induced lung injury; however, its underlying mechanisms of regulating matrix metalloproteinase-9 (MMP-9) in alveolar macrophages remain unclear. Methods: The regulatory mechanisms of naringenin in cigarette smoke extra...
ORGANISM(S): Mus Musculus 
2025-04-21 | PXD063137 |
UnknownNovel pentacyclic derivatives and benzylidenes of the progesterone series cause anti-estrogenic and antiproliferative effects and induce apoptosis in breast cancer cells.
Not available
S-EPMC9875769 | biostudies-literature
UnknownBi-allelic missense variant, p.Ser35Leu in EXOSC1 is associated with pontocerebellar hypoplasia.
Not available
S-EPMC9990822 | biostudies-literature
UnknownCytotoxicity of the Sesquiterpene Lactones Neoambrosin and Damsin from Ambrosia maritima Against Multidrug-Resistant Cancer Cells.
Not available
S-EPMC4637410 | biostudies-literature
UnknownImmunoproteomic analysis of Trichinella spiralis and Trichinella britovi excretory-secretory muscle larvae proteins recognized by sera from humans infected with Trichinella.
Not available
S-EPMC7644068 | biostudies-literature
UnknownGenetic characterization of bovine viral diarrhea virus strains in Beijing, China and innate immune responses of peripheral blood mononuclear cells in persistently infected dairy cattle.
Not available
S-EPMC4701742 | biostudies-literature
UnknownThe effect of saliva on the fate of nanoparticles.
Not available
S-EPMC5820401 | biostudies-literature
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