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UnknownIn Vivo Efficacy and Pharmacokinetics of the 2-Aminomethylphenol Antimalarial JPC-3210 in the Aotus Monkey-Human Malaria Model.
Not available
S-EPMC7038259 | biostudies-literature
UnknownCharacterization of the Preclinical Pharmacology of the New 2-Aminomethylphenol, JPC-3210, for Malaria Treatment and Prevention.
Not available
S-EPMC5913937 | biostudies-literature
ProteomicsMulti-omics analysis demonstrates unique mode of action of a potent new antimalarial compound, JPC-3210, against Plasmodium falciparum
The increasing incidence of antimalarial drug resistance to the first-line artemisinins, and their combination partner drugs, underpins an urgent need for new antimalarial drugs, ideally with a novel mechanism of action. The recently developed 2-aminomethylphenol, JPC-3210, (MMV 892646) is an erythr...
ORGANISM(S): Homo sapiens (Human) Plasmodium falciparum (isolate 3D7) 
2019-12-20 | PXD013539 | Pride
Antimalarial drug discovery Proteomics Mechanism of action Metabolomics 2-aminomethylphenol 
UnknownJPC-2997, a new aminomethylphenol with high in vitro and in vivo antimalarial activities against blood stages of Plasmodium.
Not available
S-EPMC4291346 | biostudies-literature
UnknownMulti-omic Characterization of the Mode of Action of a Potent New Antimalarial Compound, JPC-3210, Against Plasmodium falciparum.
Not available
S-EPMC7000111 | biostudies-literature
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