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MetabolomicsLipids in the escalated host-pathogen arms race

Lipids, fundamental constituents of cell membranes, cellular energy carriers, and signaling molecules, play a pivotal role in the interaction between pathogens and hosts. During microbial infections, lipids not only fuel the activation of the immune system but also, acting as signaling molec...

2025-07-05 | MTBLS12678 | MetaboLights
TranscriptomicsIdentification of genes upregulated by methyl-CpG targeted transcriptional activation (MeTA) in 293T
The identification of genes transcriptionally silenced by DNA hypermethylation is important in understanding the molecular basis of epigenetically regulated biological processes such as X chromosome inactivation, genomic imprinting, and cancer development. Our previously developed methyl-CpG targete...
ORGANISM(S): Homo sapiens 
2011-06-03 | E-GEOD-25981 | biostudies-arrayexpress
TranscriptomicsRole of BACH1 in HEK 293T cells
This SuperSeries is composed of the following subset Series: GSE28050: Expression data from knockdown of BACH1 in HEK 293T cells GSE28051: Genome-wide map of BACH1 binding in HEK293T cells Refer to individual Series
ORGANISM(S): Homo sapiens 
2011-05-12 | E-GEOD-28053 | biostudies-arrayexpress
TranscriptomicsExpression data from 293T cell treated with ROCK inhibitor
We used microarray to determine the genes whose expression was changed at three or six hours after Y27632 treatment. Three-condition experiment; 293T control vs 293T treated with Y27632 for three hours, 293T control vs 293T treated with Y27632 for six hours.
ORGANISM(S): Homo sapiens 
2014-04-21 | E-GEOD-32024 | biostudies-arrayexpress
TranscriptomicsGene Expression Profile of 293T and 293T-Aire-expressing cells
To analyze the impact of Aire on gene expression profile in a model cell line, we used 293T cells and transfected them either with an Aire expression plasmid pCMV-Aire (where mAire is driven by CMV promoter) or with a control plasmid pCMV2B. Total RNA was extracted 48 hours post transfection, proces...
ORGANISM(S): Homo sapiens 
2010-10-16 | E-GEOD-24733 | biostudies-arrayexpress
TranscriptomicshDBR1 OVEREXPRESSED CALU6 AND 293T CELLS VS. CONTROL CELLS
RNA debranching enzyme (hDBR1) is the only known enzyme to turn over lariat intron RNA during splicing. We compared the transcriptome differences between hDBR1 overexpressed and control Calu6 and 293T cells, to see its general effect on RNA splicing.
ORGANISM(S): Homo sapiens 
2017-01-25 | E-MTAB-5347 | biostudies-arrayexpress
GenomicsGenome-wide distribution of UHRF2 and ZNF618 in 293T cells.
We have identified ZNF618 as a novel binding partner of UHRF2. We have found that UHRF2 and ZNF618 co-localize at many genomic loci. Examination of genome-wide distribution of SFB-tagged UHRF2 and ZNF618 in 293T cells using ChIP-seq.
ORGANISM(S): Homo sapiens 
2016-05-31 | E-GEOD-80037 | biostudies-arrayexpress
GenomicsHomo sapiens strain:293T cells
Homo sapiens strain:293T cells Transcriptome or Gene expression
PRJNA218550 | ENA
TranscriptomicsGene expression data from HEK-293T cells transfected with miR-194 mimics
Nuclear factor κB (NF-κB) pathway plays an important role in hepatocellular carcinoma (HCC) progression. miR-194 was previously shown to reduce the induction of NF-κB activity upon addition of tumor necrosis factor α (TNFα). To clarify the molecular mechanism responsible for the effect of miR-194 on...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-70434 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human HEK-293T cells treated with a nutraceutical formula (solution-3), or vehicle-(saline solution)-treated controls
HEK-293T cells were plated (1x106 cells) and treated with a nutraceutical formula (solution-3) at 0.01x concentration or with vehicle (saline solution) as the negative control for the treatment. After 24 hours, the cells were lysed, and their RNA was extracted for RNAseq.
ORGANISM(S): Homo sapiens 
2024-06-19 | E-MTAB-13918 | biostudies-arrayexpress
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