Sort   by:  
 Page size 
MetabolomicsComparative non-targeted LC-MS metabolomic profiling of murine bone marrow-derived macrophages cultured in 2D versus 3D

Macrophages are key drivers of inflammatory and fibrotic diseases and their activation is shaped by interactions in their tissue microenvironment. However, dissecting the processes that drive immunopathology has proved challenging as traditional 2D culture methods fail to capture the complex mole...

2026-06-08 | MTBLS12917 | MetaboLights
MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
MetabolomicsFoHsf1 reprograms central metabolism via caffeine and vitamin D2 to modulate development and virulence of Fusarium oxysporum on Polygonatum kingianum
Root rot has severely affected the yield and quality of Polygonatum kingianum, and Fusarium oxysporum has been identified as the primary causal agent. To explore the virulence mechanisms of this pathogen, we performed a functional characterization of FoHsf1, a gene encoding a heat shock transcriptio...
2026-04-11 | MTBLS14221 | MetaboLights
TranscriptomicsExamination of protein expression patterns of closely related Salmonella serovars using 2D GE and MS/MS
The objective of the present investigation was to consider the level of variation in the protein expression patterns of closely related Salmonella serovars, in order to search for protein factors with levels of expression or posttranslational modifications characteristic for each serovar. For the co...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Enteritidis 
2008-02-26 | E-GEOD-8931 | biostudies-arrayexpress
UnknownOnline 2D-LC-MS/MS Platform for Analysis of Glycated Proteome.
Not available
S-EPMC5951789 | biostudies-literature
UnknownA Comprehensive 2D-LC/MS/MS Profile of the Normal Human Urinary Metabolome.
Not available
S-EPMC9497905 | biostudies-literature
MetabolomicsL-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS positive mode)

The overuse of antibiotics has made public health and safety face a serious crisis. It is urgent to develop new clinical treatment methods to combat drug-resistant bacteria to alleviate the health crisis. The efficiency of antibiotics is closely related to the metabolic state of bacteria. However...

2023-05-02 | MTBLS7711 | MetaboLights
MetabolomicsL-leucine increases the sensitivity of drug-resistant Salmonella to sarafloxacin by stimulating central carbon metabolism and increasing intracellular reactive oxygen species level (LC-MS negative mode)

The overuse of antibiotics has made public health and safety face a serious crisis. It is urgent to develop new clinical treatment methods to combat drug-resistant bacteria to alleviate the health crisis. The efficiency of antibiotics is closely related to the metabolic state of bacteria. However...

2023-05-02 | MTBLS7713 | MetaboLights
UnknownAnalysis of Antioxidant Compounds in Vitex negundo Leaves Using Offline 2D-LC-ECD and LC-MS/MS.
Not available
S-EPMC11242995 | biostudies-literature
ProteomicsIdentification of novel serum biomarkers for malignant mesothelioma using iTRAQ combined with 2D-LC-MS/MS
In this project, differential serum proteins (DEPs) were first screened in MM patients and healthy controls using iTRAQ labeling coupled with 2D LC-MS/MS method. As a result, 475 proteins were identified, of which, 327 proteins contain at least two unique peptides, and 145 DEPs were found between M...
ORGANISM(S): Homo Sapiens 
2019-10-30 | PXD016073 |
Sort   by:  
 Page size