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MetabolomicsComparative non-targeted LC-MS metabolomic profiling of murine bone marrow-derived macrophages cultured in 2D versus 3D

Macrophages are key drivers of inflammatory and fibrotic diseases and their activation is shaped by interactions in their tissue microenvironment. However, dissecting the processes that drive immunopathology has proved challenging as traditional 2D culture methods fail to capture the complex mole...

2026-06-08 | MTBLS12917 | MetaboLights
TranscriptomicsExamination of protein expression patterns of closely related Salmonella serovars using 2D GE and MS/MS
The objective of the present investigation was to consider the level of variation in the protein expression patterns of closely related Salmonella serovars, in order to search for protein factors with levels of expression or posttranslational modifications characteristic for each serovar. For the co...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Enteritidis 
2008-02-26 | E-GEOD-8931 | biostudies-arrayexpress
UnknownOnline 2D-LC-MS/MS Platform for Analysis of Glycated Proteome.
Not available
S-EPMC5951789 | biostudies-literature
UnknownA Comprehensive 2D-LC/MS/MS Profile of the Normal Human Urinary Metabolome.
Not available
S-EPMC9497905 | biostudies-literature
UnknownAnalysis of Antioxidant Compounds in Vitex negundo Leaves Using Offline 2D-LC-ECD and LC-MS/MS.
Not available
S-EPMC11242995 | biostudies-literature
ProteomicsProteomic analysis of cellular soluble proteins from human bronchial smooth muscle cells by combining nondenaturing micro 2DE and quantitative LC-MS/MS: Preparation of more than 4000 native protein maps
Soluble proteins of human bronchial smooth muscle cells (HBSMC) were separated by nondenaturing micro 2DE and a 30 mm X 40 mm area of the CBB-stained slab gel (1.0 mm thick) was cut into 1.1 mm X 1.1 mm squares, then the proteins in the 972 gel pieces (squares) were applied to quantitative LC-MS/MS....
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-23 | MSV000080002 | MassIVE
ProteomicsIdentification of novel serum biomarkers for malignant mesothelioma using iTRAQ combined with 2D-LC-MS/MS
In this project, differential serum proteins (DEPs) were first screened in MM patients and healthy controls using iTRAQ labeling coupled with 2D LC-MS/MS method. As a result, 475 proteins were identified, of which, 327 proteins contain at least two unique peptides, and 145 DEPs were found between M...
ORGANISM(S): Homo Sapiens 
2019-10-30 | PXD016073 |
ProteomicsComprehensive 2D-LC/MS/MS profile of normal human urinary metabolome
A comprehensivemetabolomics profile of normal human urine
ORGANISM(S): Homo Sapiens 
PXD035515 |
UnknownPerformance comparisons of nano-LC systems, electrospray sources and LC-MS-MS platforms.
Not available
S-EPMC3886563 | biostudies-literature
UnknownIdentification of Microbial Strains via 2D Cross-Correlation of LC-MS Data.
Not available
S-EPMC11197091 | biostudies-literature
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