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ProteomicsLabel-free, quantitative analysis of PKA-dependent phosphoproteome changes in Trypanosoma brucei
Protein kinase A (PKA), the main effector of second messenger cAMP, is highly conserved among eukaryotes and a paradigm for the mechanisms of regulation of protein kinases by ligands. The unique PKA holoenzymes in the phylogenetically distant protozoan parasite Trypanosoma are unresponsive to cAMP i...
ORGANISM(S): Trypanosoma brucei 
2019-02-25 | PXD012245 | Pride
Protein kinase a  pka  trypanosoma  7-cyano-7-deazainosine  label-free quantitative phosphoproteome analysis 
ProteomicsLabel-free quantitative analysis of PKA-dependent proteome changes in Trypanosoma brucei
Protein kinase A (PKA), the main effector of second messenger cAMP, is highly conserved among eukaryotes and a paradigm for the mechanisms of regulation of protein kinases by ligands. The unique PKA holoenzymes in the phylogenetically distant protozoan parasite Trypanosoma are unresponsive to cAMP i...
ORGANISM(S): Trypanosoma brucei 
2019-02-25 | PXD009073 | Pride
Protein kinase a 7-cyano-7-deazainosine Pka Trypanosoma Label-free quantitative proteome analysis 
UnknownNucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma.
Not available
S-EPMC6440977 | biostudies-literature
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