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ProteomicsInteraction of 7SK with the Smn complex modulates snRNP production
Gene expression requires tight coordination of the molecular machineries that mediate transcription and splicing. While the interplay between transcription kinetics and spliceosome fidelity has been investigated before, less is known about mechanisms regulating the assembly of the spliceosomal machi...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-26 | PXD021360 | Pride
Smn complex Transcription Interaction 7sk 
GenomicsSox2 is present in RNA binding complexes and interacts with snRNA 7SK in mouse embryonic stem cells
Sox2 is a master transcriptional regulator of embryonic development and has been found to interact with RNA binding proteins such as the non-coding RNA 7SK. 7SK has been shown to regulate transcription at regulatory regions, which could suggest a functional interaction with Sox2 for chromatin recrui...
ORGANISM(S): Mus musculus 
2019-05-07 | E-MTAB-7570 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of 7SK knockdown in mouse embryonic stem cells
Transcriptome profiling of mouse embryonic stem cells following antisense knockdown of the non-coding RNA 7SK.
ORGANISM(S): Mus musculus 
2013-09-09 | E-MTAB-1585 | biostudies-arrayexpress
TranscriptomicsSR Proteins Collaborate with 7SK and Promoter-Associated Nascent RNA to Release Paused Polymerase
RNAP II is frequently paused near gene promoters in mammals and its transition to productive elongation requires active recruitment of P-TEFb, a cyclin-dependent kinase for RNAP II and other key transcription elongation factors. A fraction of P-TEFb is sequestered in an inhibitory complex containing...
ORGANISM(S): Mus musculus 
2013-05-09 | E-GEOD-45517 | biostudies-arrayexpress
Genomics7SK-BAF axis controls pervasive transcription at enhancers [ChIRP-Seq]
7SK-BAF axis controls pervasive transcription at enhancers [ChIRP-Seq]
PRJNA284635 | ENA
GenomicsThe 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming
The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming
PRJNA612855 | ENA
GenomicsPseudouridylation of 7SK by PUS7 regulates Pol II transcription elongation
Pseudouridylation of 7SK by PUS7 regulates Pol II transcription elongation
PRJNA1216229 | ENA
GenomicsTranscriptional profiling of 7SK knockdown in mouse embryonic stem cells
Transcriptional profiling of 7SK knockdown in mouse embryonic stem cells
PRJEB1703 | ENA
UnknownReconstitution of a functional 7SK snRNP.
Not available
S-EPMC5499737 | biostudies-literature
UnknownProgress in 7SK ribonucleoprotein structural biology.
Not available
S-EPMC10083321 | biostudies-literature
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