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UnknownStructural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Not available
S-EPMC10026943 | biostudies-literature
MetabolomicsMultiple acyl-coA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection

The human pathogen Mycobacterium tuberculosis (Mtb) devotes a significant fraction of its genome to fatty acid metabolism. Although Mtb depends on host fatty acids as a carbon source, fatty acid b-oxidation is mediated by genetically redundant enzymes, which has hampered the development of antitu...

2021-09-29 | MTBLS2374 | MetaboLights
TranscriptomicsAnalysis of gene expression in esophageal squamous cell carcinoma (ESCC)
To characterize gene expression in esophageal squamous cell carcinoma, we examined gene expression in tumor and matched normal adjacent tissue from 17 ESCC patients from a high-risk region of China. RNA was extracted from 17 micro-dissected tumor and matched normal tissue pairs using the PureLink Mi...
ORGANISM(S): Homo sapiens 
2011-03-15 | E-GEOD-20347 | biostudies-arrayexpress
UnknownInfluence of Inhaled Amiloride on Lung Fluid Clearance in Response to Normobaric Hypoxia in Healthy Individuals.
Not available
S-EPMC5743027 | biostudies-literature
UnknownComparative outcomes of donor graft CD34+ selection and immune suppressive therapy as graft-versus-host disease prophylaxis for patients with acute myeloid leukemia in complete remission undergoing HLA-matched sibling allogeneic hematopoietic cell transplantation.
Not available
S-EPMC3434978 | biostudies-literature
ProteomicsComplexome profiling of mitochondrial protein complexes from patients with mutation in NDUFAF8 gene
NDUFAF8 is an assembly factor of the NADH:ubiquinone oxidoreductase (complex I). Here we used complexome profiling the functional consequences of NDUFAF8 mutations in patient fibroblasts.
ORGANISM(S): Homo sapiens (Human) 
2020-03-05 | PXD015749 | Pride
Oxidative phosphorylation system Lc-msms Complexome profiling Complex i assembly 
ProteomicsComplexome profiling of mitochondrial protein complexes from patients with mutation in NDUFC2 gene
NDUFC2 is a subunit of the membrane part of NADH:ubiquinone oxidoreductase (complex I). Here we used complexome profiling to study the role of NDUFC2 in complex I stability and assembly.
ORGANISM(S): Homo sapiens (Human) 
2020-08-10 | PXD014936 | Pride
Oxidative phosphorylation system Lc-msms Complexome profiling Complex i assembly 
TranscriptomicsTranscription profiling of human fibroblast RNA from a patient with a mitochondrial oxidative phosphorylation complex I deficiency vs normal fibroblast RNA
Comparison of fibroblast RNA from a patient with a mitochondrial oxidative phosphorylation comnplex I deficiency against normal fibroblast RNA.

Note: this experiment submission is not fully MIAME compliant, due to the unavailability of oligonucleotide sequences on the A-MEXP-70 array ("Adelai...
ORGANISM(S): Homo sapiens 
2004-09-01 | E-MEXP-119 | biostudies-arrayexpress
TranscriptomicsAnalysis of genomic instability in esophageal squamous cell carcinoma (ESCC)
To characterize genomic instability in esophageal squamous cell carcinoma, we examined loss of heterozygosity, copy number loss, and copy number gain in ESCC patients from a high-risk region of China. Affymetrix SNP arrays were performed according to the manufacturer's directions on DNA extracted fr...
ORGANISM(S): Homo sapiens 
2010-04-10 | E-GEOD-15526 | biostudies-arrayexpress
UnknownCorpus Callosum Integrity Relates to Improvement of Upper-Extremity Function Following Intensive Rehabilitation in Children With Unilateral Spastic Cerebral Palsy.
Not available
S-EPMC8135240 | biostudies-literature
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