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TranscriptomicsExpression profiles of a panel of MSS and MSI colon cancer cell lines
Expression profiling was used to identify genes differentially expressed in MSS (microsatellite stable) and MSI (microsatellite unstable) colon cancer cell lines. Data submitted in support of manuscript entitled Villin expression is frequently lost in poorly differentiated colon cancer, Diego Arang...
ORGANISM(S): Homo sapiens 
2012-02-07 | E-GEOD-35566 | biostudies-arrayexpress
no omics definedTranscription profiling of yeast with a fumarase point mutation or knock-out to model hereditary leiomyomatosis and renal cell cancer
Effect of fumarase point mutation or knock-out on transcriptional profile in yeast to model hereditary leiomyomatosis and renal cell cancer (HLRCC).
ORGANISM(S): Saccharomyces cerevisiae 
2006-11-29 | E-MEXP-922 | biostudies-arrayexpress
TranscriptomicsExpression data from human MSI colorectal cancer and normal colonic mucosa
Microsatellite instability (MSI), caused by defective mismatch repair, is observed in a subset of colorectal cancers (CRCs). We evaluated somatic mutations in microsatellite repeats of genes chosen based on reduced expression in MSI CRC and existence of a coding mononucleotide repeat. Expression pro...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-24514 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human uterine fibroids and normal myometrium
Defects in mitochondrial enzymes predispose to severe developmental defects as well as tumorigenesis. Heterozygous germline mutations in the nuclear gene encoding fumarate hydratase (FH), an enzyme catalyzing the hydration of fumarate in the Krebs tricarboxylic acid cycle, cause hereditary leiomyoma...
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-2724 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human fibriods vs. normal myometrium with mutated or wild type fumarate hydratase (FH) gene reveals distinct expression profiles in fumarate-hydratase-deficient uterine fibroids.
A series of gene expression measurements of normal myometrium and uterine fibroids with mutated or wild-type fumarate hydratase (FH) gene.
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-2725 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human uterine fibroids with mutated or wild type fumarate hydratase gene
A series of gene expression measurements of uterine fibroids with mutated or wild-type fumarate hydratase (FH) gene.
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-2152 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of proficient versus microRNA processing human colon cancer cell lines
MicroRNA expression signatures of TARBP2 and empty vector Co115 transfected cells (colon cancer)
ORGANISM(S): Homo sapiens 
2010-01-28 | E-MTAB-83 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human primary colorectal cancers
Samples were taken from colorectal cancers in surgically resected specimens from 74 patients. The expression profiles were determined using Affymetrix Human Genome U133Plus 2.0 arrays. Our MSI/MSS classifer was applied to these samples. Experiment Overall Design: mRNA from 74 fresh-frozen primary co...
ORGANISM(S): Homo sapiens 
2009-01-16 | E-GEOD-13067 | biostudies-arrayexpress
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