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TranscriptomicsGene expression and muscle fiber function in a porcine ICU model
Background: Skeletal muscle wasting and impaired muscle function in response to mechanical ventilation and immobilization in intensive care unit (ICU) patients are clinically challenging partly due to (i) the poorly understood intricate cellular and molecular networks; and (ii) the unavailability of...
ORGANISM(S): Sus scrofa 
2009-08-31 | E-GEOD-16348 | biostudies-arrayexpress
TranscriptomicsThe function of corticosteriods in the development of limb muscle weakness in a porcine ICU model
Background: The aim of this study is to improve our understanding of the mechanisms underlying the function of corticosteriods in the limb muscles of ICU patients with acute quadriplegic myopathy (AQM) by using a unique porcine ICU model, i.e., 5-day longitudinal experiments where animals are sedate...
ORGANISM(S): Sus scrofa 
2012-04-11 | E-GEOD-37166 | biostudies-arrayexpress
TranscriptomicsProstate Cancer Gene Expression Changes after Treatment with Neoadjuvant Dutasteride
To identify molecular changes underlying the chemopreventive or tumor promoting effects of SRD5A inhibition, we profiled gene expression changes in benign prostate epithelium from patients with PCa treated with dutasteride, a dual SRD5A inhibitor. Subjects were aged 45-80 years with clinically local...
ORGANISM(S): Homo sapiens 
2008-12-01 | E-GEOD-9972 | biostudies-arrayexpress
TranscriptomicsProstate Cancer Gene Expression Changes with Neoadjuvant Hormone Therapy
Men with clinically localized prostate cancer were treated with 0 to 9 months of neoadjuvant hormone suppression prior to prostatectomy. Keywords: microarray, hormone, 9 men with prostate cancer were assigned to neoadjuvant hormone suppression therapy for 3-6, 6, or 0 months.
ORGANISM(S): Homo sapiens 
2008-12-01 | E-GEOD-9983 | biostudies-arrayexpress
UnknownRescue PCI in the management of STEMI: Contemporary results from the Melbourne Interventional Group registry.
Not available
S-EPMC7988313 | biostudies-literature
TranscriptomicsThe role of sepsis in the development of limb muscle weakness in a porcine ICU model
Background : The aim of this study is to improve our understanding of the mechanisms underlying the role of sepsis in the limb muscles of ICU patients with acute quadriplegic myopathy (AQM) by using a unique porcine ICU model, i.e., 5-day longitudinal experiments where animals are sedated, mechanica...
ORGANISM(S): Sus scrofa 
2011-10-18 | E-GEOD-33037 | biostudies-arrayexpress
UnknownMultimorbidity and the risk of malnutrition, frailty and sarcopenia in adults with cancer in the UK Biobank.
Not available
S-EPMC11446695 | biostudies-literature
GenomicsAcquired Copy Number Alterations in Adult Acute Myeloid Leukemia Genomes

We performed genome-wide copy number analysis with paired normal and tumor DNA obtained from 86 adult patients with de novo AML using the Affymetrix Genome-Wide Human SNP array 6.0 containing 1.85 million features. Acquired copy number alterations (CNA) were confirmed using an independent, hig...

phs000201.v1.p1 | EGA
UnknownCD8+ tumor-infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival.
Not available
S-EPMC7484874 | biostudies-literature
MetabolomicsMulti-Omics Approach to Elucidate Cerebrospinal Fluid Changes in Dogs with Intervertebral Disc Herniation
Herniation of the intervertebral disc (IVDH) is the most common cause of neurological and intervertebral disc degeneration-related diseases. Since the disc starts to degenerate before it can be observed by currently available diagnostic methods, there is an urgent need for novel diagnostic approache...
2021-11-04 | MTBLS2689 | MetaboLights
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