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ProteomicsAmple glycosylation in membrane and cell envelope protein explains phenotypic diversity, virulence and AMR in the Mycobacterium tuberculosis complex
Glycoproteomics is likely to identify Mtb virulence factors because glycoproteins on the bacterial cell envelope are used by mycobacteria to enter the primary human host cell, the macrophage. It has been proposed that Mtb interacts with mannose receptors on host cells via mannosylated proteins to en...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2019-03-25 | PXD009676 | Pride
Glycosylation Phenotypic variability Ptms Virulence Glycoproteomics M. tuberculosis 
ProteomicsComparative Proteomic Analysis of the Mycobacterium tuberculosis Lineage 7 Reveals Differentially Abundant Proteins Linked to Slow Growth
Differentially abundant proteins were quantified in the slowly growing Mycobacterium tuberculosis (M. tuberculosis) lineage 7 strains and the M. tuberculosis lineage 4 reference strain H37Rv. Mass spectrometry based proteomic analysis was employed to identify, quantitate and compare the protein pro...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2017-05-24 | PXD006117 | Pride
Proteomics Mycobacterium tuberculosis Tuberculosis Lineage 7 Mass spectrometry Ethiopia Type 7 secretion 
ProteomicsLineage-Specific Proteomic Signatures in the Mycobacterium Tuberculosis Complex Reveal Differential Abundance of Proteins Involved in Virulence, DNA Repair, CRISPR-Cas, Bioenergetics and Lipid Metabolism
Despite the discovery of Mycobacterium tuberculosis (Mtb) more than 130 years ago, Mtb physiology and the mechanisms of virulence are still not fully understood. The objective of this study was to compare and characterize the differentially abundant protein profiles of modern, pre-modern and ancient...
ORGANISM(S): Mycobacterium tuberculosis 
2020-09-01 | PXD020383 | Pride
Proteomics Virulence Esx-3 secretion system Dna repair Mycobacterium tuberculosis  lineage 7 Ethiopia 
UnknownRetention in Care of Adult HIV Patients Initiating Antiretroviral Therapy in Tigray, Ethiopia: A Prospective Observational Cohort Study.
Not available
S-EPMC4560381 | biostudies-literature
UnknownMeasuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017.
Not available
S-EPMC6227911 | biostudies-literature
UnknownGlobal, regional, and national burden of disorders affecting the nervous system, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
Not available
S-EPMC10949203 | biostudies-literature
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