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MetabolomicsIntegrated multi-omics analysis of liver metabolic dysregulation in ACE2 knockout mice
This study systematically investigated the impact of ACE2 knockout (ACE2KO) on hepatic metabolic homeostasis and its molecular mechanisms, using integrated transcriptomic, proteomic, and metabolomic profiling. ACE2 deficiency exacerbates hepatic lipid accumulation, as evidenced by elevated total cho...
2025-06-23 | MTBLS12389 | MetaboLights
GenomicsSynechococcus sp. Ace-Pa
Synechococcus sp. Ace-Pa Genome sequencing and assembly
PRJNA536950 | ENA
MetabolomicsPomegranate Peel Extract as an Inhibitor of SARS-CoV-2 Spike Binding to Human ACE2 Receptor (in vitro): A Promising Source of Novel Antiviral Drugs
Plant extracts are rich in bioactive compounds, such as polyphenols, sesquiterpenes, and triterpenes, which potentially have antiviral activities. As a consequence of the coronavirus disease 2019 pandemic, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus, thousands of...
2021-10-06 | MTBLS2309 | MetaboLights
TranscriptomicsHippocampal gene expression profiling of a model of Alzheimer`s Disease upon treatment with the ACE inhibitor captopril
Extracellular senile plaques of amyloid beta (Abeta) are a pathological hallmark in brain of patients with Alzheimer`s Disease (AD). Abeta is generated by the amyloidogenic processing of the amyloid precursor protein (APP). Concomitant to Abeta load, AD brain is characterized by an increase in prote...
ORGANISM(S): Mus musculus 
2013-05-14 | E-GEOD-46871 | biostudies-arrayexpress
GenomicsAcinetobacter schindleri strain:ACE
Acinetobacter schindleri ACE Genome sequencing and assembly
PRJNA320745 | ENA
ProteomicsThe Plethora of Angiotensin-Converting Enzyme Substrates in Mouse Plasma
Angiotensin converting enzyme (ACE) is known for converting inactive angiotensin I into the potent vasoconstrictor angiotensin II, playing a critical role in blood pressure regulation. However, there is evidence that the dicarboxypeptidase activity of ACE is also essential for other physiological pr...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-12 | PXD010258 | Pride
Peptidomics 
GenomicsMethanogenium frigidum Ace-2
This marine archaeon was collected from Vestfold Hills, Antarctica at a depth of 24 meters.
PRJNA13497 | ENA
ProteomicsLC-MS/MS identification and sequence analysis of ACE inhibitory peptides derived from bovine hemoglobin
This project contains raw MS data and database search files for the identification and sequence analysis of ACE inhibitory peptides derived from bovine hemoglobin using LC-MS/MS. The data includes original mass spectrometry files and corresponding search results for peptide identification and sequen...
ORGANISM(S): Bos Taurus 
2026-03-27 | PXD076229 |
TranscriptomicsGene expression in primary erythroid cells and in bone marrow stromal cells following treatment with Sotatercept (ACE-011)
Gene expression in primary erythroid cells and in bone marrow stromal cells following treatment with Sotatercept (ACE-011) Gene expression profiles of erythroid cells derived from human CD34+ cells generated under standard conditions and in cultures containing conditioned media from bone marrow stro...
ORGANISM(S): Homo sapiens 
2012-10-20 | E-GEOD-41708 | biostudies-arrayexpress
TranscriptomicsACE-Scan of the ATP RNA aptamer on 10^12 Gen1 DNA microarray
The experiments were carried out to map the ligand binding landscape of various DNA and RNA duplexed aptamer families. Duplexed Aptamer (DA) constructs were engineered from (i) natural and synthetic DNA and RNA aptamers and (i) synthetic oligonucleotide aptamer-complementary elements synthesized on ...
ORGANISM(S): synthetic construct 
2017-12-20 | E-MTAB-6376 | biostudies-arrayexpress
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