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ProteomicsEngineered transfer RNAs for suppression of premature termination codons
PTCs cause a multitude of human diseases and there are no established therapeutic options for their therapeutic management. Herein, we report the high-throughput cloning and identification, characterization and functional analysis of anticodon-edited tRNA which display efficacious PTC reversion in ...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2019-02-11 | PXD012581 | Pride
Anticodon edited trnas Ptc repair Ace-trnas 
UnknownOptimization of ACE-tRNAs function in translation for suppression of nonsense mutations.
Not available
S-EPMC11662937 | biostudies-literature
UnknownAnticodon Edited Transfer RNAs (ACE-tRNAs) Encoded as Therapeutic Nonviral Minimal DNA Vectors.
Not available
S-EPMC12424623 | biostudies-literature
ProteomicsAnticodon Engineered Transfer RNA (tRNASUAG) Inhibits Hepatitis B Virus Replication by Promoting Degradation of the Core Protein
Current antiviral drugs targeting hepatitis B virus (HBV) still face challenges in achieving functional cure for chronic hepatitis B. Therefore, it is necessary to explore new therapeutic approaches and combination therapy strategies. Anticodon engineered transfer RNA (ACE-tRNA) has been widely appl...
ORGANISM(S): Homo sapiens (Human) 
2025-12-08 | PXD063150 | Pride
Anticodon engineered transfer rna  trnasuag  hepatitis b virus  core protein  ace-trna-grna tandem array 
UnknownA novel viral vaccine platform based on engineered transfer RNA.
Not available
S-EPMC9769134 | biostudies-literature
UnknownAnticodon-edited tRNA enables translational readthrough of COL4A5 premature termination codons.
Not available
S-EPMC12716684 | biostudies-literature
UnknownEfficient suppression of endogenous CFTR nonsense mutations using anticodon-engineered transfer RNAs.
Not available
S-EPMC9126842 | biostudies-literature
UnknownAnticodon Engineered Transfer RNA (tRNA<sup>SUAG</sup>) Inhibits Hepatitis B Virus Replication by Promoting the Degradation of Core Protein.
Not available
S-EPMC12677619 | biostudies-literature
UnknownEngineered tRNAs efficiently suppress CDKL5 premature termination codons.
Not available
S-EPMC11685654 | biostudies-literature
UnknownEngineered transfer RNAs for suppression of premature termination codons.
Not available
S-EPMC6379413 | biostudies-literature
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